Comorbidities, multimorbidity and COVID-19

CD Russell, NI Lone, JK Baillie - Nature medicine, 2023 - nature.com
The influence of comorbidities on COVID-19 outcomes has been recognized since the
earliest days of the pandemic. But establishing causality and determining underlying …

Diabetes and multiple long-term conditions: A review of our current global health challenge

K Khunti, YV Chudasama, EW Gregg… - Diabetes …, 2023 - Am Diabetes Assoc
Use of effective treatments and management programs is leading to longer survival of
people with diabetes. This, in combination with obesity, is thus contributing to a rise in …

[HTML][HTML] Comprehensive review of COVID-19: epidemiology, pathogenesis, advancement in diagnostic and detection techniques, and post-pandemic treatment …

YS Chung, CY Lam, PH Tan, HF Tsang… - International Journal of …, 2024 - mdpi.com
At present, COVID-19 remains a public health concern due to the ongoing evolution of
SARS-CoV-2 and its prevalence in particular countries. This paper provides an updated …

Ethnic disparities in COVID-19 outcomes: a multinational cohort study of 20 million individuals from England and Canada

F Zaccardi, PS Tan, BR Shah, K Everett, AK Clift… - BMC Public Health, 2023 - Springer
Background Heterogeneous studies have demonstrated ethnic inequalities in the risk of
SARS-CoV-2 infection and adverse COVID-19 outcomes. This study evaluates the …

Expert consensus: main risk factors for poor prognosis in COVID-19 and the implications for targeted measures against SARS-CoV-2

FJ Candel, P Barreiro, M Salavert, A Cabello… - Viruses, 2023 - mdpi.com
The clinical evolution of patients infected with the Severe Acute Respiratory Coronavirus
type 2 (SARS-CoV-2) depends on the complex interplay between viral and host factors. The …

[HTML][HTML] A Digital Tool for Clinical Evidence–Driven Guideline Development by Studying Properties of Trial Eligible and Ineligible Populations: Development and …

S Mumtaz, M McMinn, C Cole, C Gao, C Hall… - Journal of medical …, 2025 - jmir.org
Background Clinical guideline development preferentially relies on evidence from
randomized controlled trials (RCTs). RCTs are gold-standard methods to evaluate the …

[HTML][HTML] The intertwining of healthcare-associated infections and COVID-19 in Italian intensive care units: An analysis of the SPIN-UTI project from 2006 to 2021

M Barchitta, A Maugeri, G Favara, RM San Lio… - Journal of Hospital …, 2023 - Elsevier
Background Although healthcare-associated infections (HAIs) pose an extraordinary burden
on public health, the impact of coronavirus disease 2019 (COVID-19) is still a matter of …

A qualitative exploration of barriers to efficient and effective structured medication reviews in primary care: findings from the DynAIRx study

AS Abuzour, SA Wilson, AA Woodall, FS Mair, A Clegg… - Plos one, 2024 - journals.plos.org
Introduction Structured medication reviews (SMRs), introduced in the United Kingdom (UK)
in 2020, aim to enhance shared decision-making in medication optimisation, particularly for …

Maternal multimorbidity and preterm birth in Scotland: an observational record-linkage study

A Azcoaga-Lorenzo, AF Fagbamigbe, U Agrawal… - BMC medicine, 2023 - Springer
Background Multimorbidity is common in women across the life course. Preterm birth is the
single biggest cause of neonatal mortality and morbidity. We aim to estimate the prevalence …

Trends in COVID-19 hospital outcomes in England before and after vaccine introduction, a cohort study

PD Kirwan, A Charlett, P Birrell, S Elgohari… - Nature …, 2022 - nature.com
Widespread vaccination campaigns have changed the landscape for COVID-19, vastly
altering symptoms and reducing morbidity and mortality. We estimate trends in mortality by …