Natural killer (NK) cells are potent immune effector cells that can respond to infection and cancer, as well as allowing maternal adaptation to pregnancy. In response to malignant …
L Pedersen, M Idorn, GH Olofsson, B Lauenborg… - Cell metabolism, 2016 - cell.com
Regular exercise reduces the risk of cancer and disease recurrence. Yet the mechanisms behind this protection remain to be elucidated. In this study, tumor-bearing mice randomized …
▪ Abstract Macrophages express a broad range of plasma membrane receptors that mediate their interactions with natural and altered-self components of the host as well as a range of …
I Waldhauer, A Steinle - Oncogene, 2008 - nature.com
Natural killer (NK) cells are lymphocytes of the innate immune system that monitor cell surfaces of autologous cells for an aberrant expression of MHC class I molecules and cell …
Natural killer (NK) cells, similar to other lymphocytes, acquire tolerance to self. This means that NK cells have the potential to attack normal self cells but that there are mechanisms to …
PA Lang, KS Lang, HC Xu, M Grusdat… - Proceedings of the …, 2012 - National Acad Sciences
Infections with HIV, hepatitis B virus, and hepatitis C virus can turn into chronic infections, which currently affect more than 500 million patients worldwide. It is generally thought that …
It is widely believed that self-tolerance of natural killer (NK) cells occurs because each NK cell expresses at least one inhibitory receptor specific for a host major histocompatibility …
AG Freud, MA Caligiuri - Immunological reviews, 2006 - Wiley Online Library
Our understanding of human natural killer (NK) cell development lags far behind that of human B‐or T‐cell development. Much of our recent knowledge of this incomplete picture …