Genetics and epigenetics of atopic dermatitis: an updated systematic review

MJ Martin, M Estravís, A García-Sánchez, I Dávila… - Genes, 2020 - mdpi.com
Background: Atopic dermatitis is a common inflammatory skin disorder that affects up to 15–
20% of the population and is characterized by recurrent eczematous lesions with intense …

Diagnostic interpretation of genetic studies in patients with primary immunodeficiency diseases: a working group report of the Primary Immunodeficiency Diseases …

IK Chinn, AY Chan, K Chen, J Chou, MJ Dorsey… - Journal of Allergy and …, 2020 - Elsevier
Genetic testing has become an integral component of the diagnostic evaluation of patients
with suspected primary immunodeficiency diseases. Results of genetic testing can have a …

Epigenome-wide association study reveals longitudinally stable DNA methylation differences in CD4+ T cells from children with IgE-mediated food allergy

D Martino, JE Joo, A Sexton-Oates, T Dang, K Allen… - Epigenetics, 2014 - Taylor & Francis
Food allergy is mediated by a combination of genetic and environmental risk factors,
potentially mediated by epigenetic mechanisms. CD4+ T-cells are key drivers of the allergic …

The pathophysiology of the hygiene hypothesis

E Prokopakis, A Vardouniotis, H Kawauchi… - International journal of …, 2013 - Elsevier
There has been a considerable increase in the diagnosis of allergic diseases over the last
decades. Prevalence of allergies in high-income countries and urban areas appears higher …

Maternal hookworm modifies risk factors for childhood eczema: results from a birth cohort in Uganda

H Mpairwe, J Ndibazza, EL Webb… - Pediatric Allergy and …, 2014 - Wiley Online Library
Background Worms may protect against allergy. Early‐life worm exposure may be critical,
but this has not been fully investigated. Objectives To investigate whether worms in …

Immunological and genetic aspects of asthma and allergy

AM Madore, C Laprise - Journal of asthma and allergy, 2010 - Taylor & Francis
Prevalence of allergy and allergic asthma are increasing worldwide. More than half of the
US population has a positive skin prick test and approximately 10% are asthmatics. Many …

Environmental epigenetics and allergic diseases: recent advances

JS Kuriakose, RL Miller - Clinical & Experimental Allergy, 2010 - Wiley Online Library
Significant strides in the understanding of the role of epigenetic regulation in asthma and
allergy using both epidemiological approaches as well as experimental ones have been …

PTGDR gene in asthma: a functional, genetic, and epigenetic study

M Isidoro‐García, C Sanz, V García‐Solaesa… - Allergy, 2011 - Wiley Online Library
To cite this article: Isidoro‐García M, Sanz C, García‐Solaesa V, Pascual M, Pescador DB,
Lorente F, Dávila I. PTGDR gene in asthma: a functional, genetic, and epigenetic study …

[PDF][PDF] Asma: concepto, fisiopatología, diagnóstico y clasificación

SG de la Rubia, SP Sánchez - PediatríaIntegral, 2012 - pediatriaintegral.es
El asma es una de las enfermedades crónicas más frecuentes en la infancia. Supone un
problema de salud grave a nivel mundial, dado el aumento de su prevalencia, de los costes …

Pharmacogenetics and the treatment of asthma

M Isidoro-García, A Sánchez-Martín… - …, 2017 - Taylor & Francis
Heterogeneity defines both the natural history of asthma as well as patient's response to
treatment. Pharmacogenomics contribute to understand the genetic basis of drug response …