Deciphering the tumor immune microenvironment from a multidimensional omics perspective: insight into next-generation CAR-T cell immunotherapy and beyond

Z Zhou, J Wang, J Wang, S Yang, R Wang, G Zhang… - Molecular Cancer, 2024 - Springer
Tumor immune microenvironment (TIME) consists of intra-tumor immunological components
and plays a significant role in tumor initiation, progression, metastasis, and response to …

Simplifying Data Analysis in Biomedical Research: An Automated, User-Friendly Tool

R Araújo, L Ramalhete, A Viegas… - Methods and …, 2024 - mdpi.com
Robust data normalization and analysis are pivotal in biomedical research to ensure that
observed differences in populations are directly attributable to the target variable, rather than …

Virtual patient analysis identifies strategies to improve the performance of predictive biomarkers for PD-1 blockade

T Arulraj, H Wang, A Deshpande, R Varadhan… - bioRxiv, 2024 - biorxiv.org
Patients with metastatic triple-negative breast cancer (TNBC) show variable responses to
PD-1 inhibition. Efficient patient selection by predictive biomarkers would be desirable, but is …