The intestinal epithelium is a critical component of the gut barrier. Composed of a single
layer of intestinal epithelial cells (IECs) held together by tight junctions, this delicate structure …

There is increasing interest in nonrodent translational models for the study of human
disease. The pig, in particular, serves as a useful animal model for the study of …

The gut barrier, composed of a single layer of intestinal epithelial cells (IECs) held together
by tight junctions, prevents the entrance of harmful microorganisms, antigens and toxins …

Significant advances in intestinal stem cell biology have been made in murine models;
however, anatomical and physiological differences between mice and humans limit mice as …

Abstract Objective Chinese Herb QingBai decoction (QBD) has been approved affective in
the treatment of IBD patients in clinic. However, the underlying mechanism remains …

The inhibitor of apoptosis (IAP) family members, notably cIAP1, cIAP2, and XIAP, are critical
and universal regulators of tumor necrosis factor (TNF) mediated survival, inflammatory, and …

Giardia lamblia, Cryptosporidium sp., and Entamoeba histolytica are important pathogenic
intestinal parasites and are amongst the leading causes worldwide of diarrheal illness in …

Cryptosporidium host cell interaction remains fairly obscure compared with other
apicomplexans such as Plasmodium or Toxoplasma. The reason for this is probably the …

Infection with the protozoan parasite Cryptosporidium parvum (CP) causes
cryptosporidiosis, a widespread diarrhoeal disease. Impaired intestinal epithelial barrier …

Cryptosporidium parvum infects intestinal epithelial cells and is commonly the parasite
species involved in mammalian cryptosporidiosis, a major health problem for humans and …