Atioxidative protection by melatonin: Multiplicity of mechanisms from radical detoxification to radical avoidance

R Hardeland - Endocrine, 2005 - Springer
Melatonin has been shown to protect against oxidative stress in various, highly divergent
experimental systems. There are many reasons for its remarkable protective potential …

Circadian rhythms, oxidative stress, and antioxidative defense mechanisms

R Hardeland, A Coto‐Montes… - Chronobiology …, 2003 - Taylor & Francis
Endogenous circadian and exogenously driven daily rhythms of antioxidative enzyme
activities and of low molecular weight antioxidants (LMWAs) are described in various …

Role of transposable elements in heterochromatin and epigenetic control

Z Lippman, AV Gendrel, M Black, MW Vaughn… - Nature, 2004 - nature.com
Heterochromatin has been defined as deeply staining chromosomal material that remains
condensed in interphase, whereas euchromatin undergoes de-condensation …

Reciprocal regulation of haem biosynthesis and the circadian clock in mammals

K Kaasik, C Chi Lee - Nature, 2004 - nature.com
The circadian clock is the central timing system that controls numerous physiological
processes. In mammals, one such process is haem biosynthesis, which the clock controls …

Mutation of the Circadian Clock Gene Per2 Alters Vascular Endothelial Function

H Viswambharan, JM Carvas, V Antic, A Marecic… - Circulation, 2007 - Am Heart Assoc
Background—The circadian clock regulates biological processes including cardiovascular
function and metabolism. In the present study, we investigated the role of the circadian clock …

Circadian clocks and vascular function

GK Paschos, GA FitzGerald - Circulation research, 2010 - Am Heart Assoc
The circadian clock regulates many aspects of physiology, including cardiovascular function.
Internal oscillators exist in endothelial, smooth muscle cells, and fibroblasts of the …

Time of day as a critical variable in biology

RJ Nelson, JR Bumgarner, JA Liu, JA Love… - BMC biology, 2022 - Springer
Background Circadian rhythms are important for all aspects of biology; virtually every aspect
of biological function varies according to time of day. Although this is well known, variation …

Evidence supporting a circadian control of natural killer cell function

A Arjona, DK Sarkar - Brain, behavior, and immunity, 2006 - Elsevier
Natural killer (NK) cells participate in the immune response against infection and cancer. An
emerging body of epidemiological data supports that circadian homeostasis may constitute …

Pharmacological Approaches to Hearing Loss

CR Cederroth, J Dyhrfjeld-Johnsen, B Canlon… - Pharmacological …, 2024 - Elsevier
Hearing disorders pose significant challenges to individuals experiencing them and their
overall quality of life, emphasizing the critical need for advanced pharmacological …

The days and nights of cancer cells

L Canaple, T Kakizawa, V Laudet - Cancer Research, 2003 - AACR
Biological clocks are intrinsic time-keeping systems that regulate behavior and physiological
functions in most living organisms. Recent works in this area have addressed possible …