Telmisartan and/or chlorogenic acid attenuates fructose-induced non-alcoholic fatty liver disease in rats: implications of cross-talk between angiotensin, the …

I Alqarni, YA Bassiouni, AM Badr, RA Ali - Biochemical Pharmacology, 2019 - Elsevier
Renin-angiotensin-aldosterone system (RAS) has been implicated in non-alcoholic fatty
liver disease (NAFLD); the most common cause of chronic liver diseases. There is …

[HTML][HTML] Protective mechanisms of telmisartan against hepatic ischemia/reperfusion injury in rats may involve PPARγ-induced TLR4/NF-κB suppression

MA Morsy, SA Abdel-Gaber, RA Rifaai… - Biomedicine & …, 2022 - Elsevier
Hepatic ischemia-reperfusion (I/R) is an important cause of liver damage in many clinical
situations. Toll-like receptor 4 (TLR4)/nuclear factor-kappa B (NF-κB) is an inflammatory …

The Protective Properties of the Strawberry (Fragaria ananassa) against Carbon Tetrachloride-Induced Hepatotoxicity in Rats Mediated by Anti-Apoptotic and …

SS Hamed, NA Al-Yhya, MF El-Khadragy… - Frontiers in …, 2016 - frontiersin.org
The strawberry (Fragaria ananassa) has been extensively used to treat a wide range of
ailments in many cultures. The present study was aimed at evaluating the hepatoprotective …

Diallyl sulfide ameliorates carbon tetrachloride‐induced hepatotoxicity in rats via suppressing stress‐activated MAPK signaling pathways

A Elkhoely - Journal of Biochemical and Molecular Toxicology, 2019 - Wiley Online Library
The underlined effects of diallyl sulfide (DAS) against CCL4‐induced oxidative,
inflammatory, and apoptotic acute hepatic damage were assessed. Administration of DAS …

Antifibrotic action of telmisartan in experimental carbon tetrachloride-induced liver fibrosis in Wistar rats.

FE Ionică, LŢ Mogoantă, GC Nicola… - Romanian Journal of …, 2016 - europepmc.org
Materials and methods In this research, we used two groups of Wistar rats, which received
intraperitoneal (ip) injection of carbon tetrachloride (CCl4) 40% dissolved in olive oil, twice …

Scavenging free radicals and soaring osteoinduction by extra cellular matrix protein–based nanocomposites on degenerative bone treatments

K Kandiah, N Duraisamy, V Amirthalingam… - Materials Science and …, 2017 - Elsevier
A number of materials are now available to alleviate the ever-growing bone disruption.
However, these are inadequate and inappropriate for addressing issues associated natural …

Hepatoprotective Activity of Rubia tinctorum's Extract against CCl4 Induced Hepatic Injury in Rats

F Marhoume, Y Zaid, H Boufous… - European Journal …, 2017 - archive.article4submit.com
This study investigated the hepatoprotective activity of Rubia tinctorum's extract against
CCl4 induced liver damage in rats. Twenty four rats were divided into four groups. Group I …

[PDF][PDF] Therapeutic effects of melatonin and quercetin on carbon tetrachloride-induced cardiac damage in rats

H Elbe, M Esrefoglu, A Taslidere… - J. Turgut Ozal Med …, 2016 - researchgate.net
Abstract Aim: Carbon tetrachloride (CCl4) is a potent, lipid-soluble toxic agent and produces
peroxidative degeneration in many tissues. In this study, antioxidative effects of melatonin …

[PDF][PDF] Protective mechanisms of telmisartan against hepatic ischemia/reperfusion injury in rats may involve PPARγ-induced TLR4/NF-κB suppression

SA Abdel-Gaber, MA Morsy, RA Rifaai… - researchgate.net
Hepatic ischemia-reperfusion (I/R) is an important cause of liver damage in many clinical
situations. Toll-like receptor 4 (TLR4)/nuclear factor-kappa B (NF-κB) is an inflammatory …

In vitro evaluation of protective effect of telmisartan on arsenic-induced genotoxicity

N Khorsandi, M Etebari - Journal of Isfahan Medical School, 2018 - jims.mui.ac.ir
Background: Drinking of arsenic-contaminated water is one the most important ways of
exposing human to this element, considering that as a substantial risk factor for the …