Background Liver, as a vital organ, is responsible for a wide range of biological functions to
maintain homeostasis and any type of damages to hepatic tissue contributes to disease …

YAP and TAZ are intracellular messengers communicating multiple interacting extracellular
biophysical and biochemical cues to the transcription apparatus in the nucleus and back to …

Serum levels of miR-194 have been reported to predict prostate cancer recurrence after
surgery, but its functional contributions to this disease have not been studied. Herein, it is …

Skeletal muscle development and growth regulatory mechanism is the focus of both animal
genetics and medicine. The recent studies indicate that covalently closed circular RNAs …

The incidence of liver disease is increasing globally. The only curative therapy for severe
end-stage liver disease, liver transplantation, is limited by the shortage of organ donors. In …

Background Nonalcoholic fatty liver disease (NAFLD) is the main cause for hepatocellular
carcinoma (HCC). This study was intended to identify the function of long non-coding RNA …

A type of small noncoding RNAs known as microRNAs (miRNAs) fine‐tune gene expression
posttranscriptionally by binding to certain messenger RNA targets. Numerous physiological …

Drug-induced liver injury (DILI) is one of the leading causes of clinical trial failures and high
drug attrition rates. Currently, the commonly used hepatocyte models include primary human …

The Yes-associated protein 1 (YAP1), a major downstream effector of the Hippo pathway,
functions as a transcriptional regulator and has an important role in cellular control of organ …

Efficiently driving chondrogenic differentiation of bone marrow mesenchymal stem cells
(BMSCs) while avoiding undesired hypertrophy remains a challenge in the field of cartilage …