Aldehyde dehydrogenase 2 as a therapeutic target in oxidative stress-related diseases: post-translational modifications deserve more attention
J Gao, Y Hao, X Piao, X Gu - International journal of molecular sciences, 2022 - mdpi.com
Aldehyde dehydrogenase 2 (ALDH2) has both dehydrogenase and esterase activity; its
dehydrogenase activity is closely related to the metabolism of aldehydes produced under …
dehydrogenase activity is closely related to the metabolism of aldehydes produced under …
Highly Selective Physical/Chemical CO2 Separation by Functionalized Fe3O4 Nanoparticles in Hollow Fiber Membrane Contactors: Experimental and Modeling …
M Rasaie, A Elhambakhsh, M Eskandari… - Energy & …, 2022 - ACS Publications
Herein, different water-based modified magnetite nanodispersions of Fe3O4-proline (Fe3O4-
P), Fe3O4-lysine (Fe3O4-L), Fe3O4@ SiO2-proline (Fe3O4@ SiO2-P), and Fe3O4@ SiO2 …
P), Fe3O4-lysine (Fe3O4-L), Fe3O4@ SiO2-proline (Fe3O4@ SiO2-P), and Fe3O4@ SiO2 …
Noncovalent Inhibition and Covalent Inactivation of Proline Dehydrogenase by Analogs of N-Propargylglycine
The flavoenzyme proline dehydrogenase (PRODH) catalyzes the first step of proline
catabolism, the oxidation of l-proline to Δ1-pyrroline-5-carboxylate. The enzyme is a target …
catabolism, the oxidation of l-proline to Δ1-pyrroline-5-carboxylate. The enzyme is a target …
Future Directions for Efficient Carbon Dioxide Separation Using Advanced Nanoparticle-Based Technologies: A Critical Review
A Elhambakhsh, P Keshavarz - Energy & Fuels, 2024 - ACS Publications
Recent advances in nanofluid-based separation of carbon dioxide (CO2) have brought
brilliant chances to shift conventional absorbents to a green, sustainable, and efficient type …
brilliant chances to shift conventional absorbents to a green, sustainable, and efficient type …
Structure-affinity relationships of reversible proline analog inhibitors targeting proline dehydrogenase
Proline dehydrogenase (PRODH) catalyzes the first step of proline catabolism, the FAD-
dependent oxidation of L-proline to Δ1-pyrroline-5-carboxylate. PRODH plays a central role …
dependent oxidation of L-proline to Δ1-pyrroline-5-carboxylate. PRODH plays a central role …
[HTML][HTML] Crystallographic Fragment Screening of a Bifunctional Proline Catabolic Enzyme Reveals New Inhibitor Templates for Proline Dehydrogenase and L …
The proline catabolic pathway consisting of proline dehydrogenase (PRODH) and L-
glutamate-γ-semialdehyde (GSAL) dehydrogenase (GSALDH) catalyzes the four-electron …
glutamate-γ-semialdehyde (GSAL) dehydrogenase (GSALDH) catalyzes the four-electron …
Biochemical, structural, and cellular characterization of S-but-3-yn-2-ylglycine as a mechanism-based covalent inactivator of the flavoenzyme proline dehydrogenase
The mitochondrial flavoenzymes proline dehydrogenase (PRODH) and hydroxyproline
dehydrogenase (PRODH2) catalyze the first steps of proline and hydroxyproline catabolism …
dehydrogenase (PRODH2) catalyze the first steps of proline and hydroxyproline catabolism …
[HTML][HTML] Construction of Trans-4-hydroxy-L-proline-producing Escherichia coli and Optimization of Fermentation Conditions
X Yang, X Li, Y Wang, Y Liu, F Wang, N Sun, C Ye - Fermentation, 2025 - mdpi.com
In this study, we combined the citric acid cycle with the biosynthesis pathways of L-proline
and L-hydroxyproline to construct a strain that produces L-hydroxyproline directly from …
and L-hydroxyproline to construct a strain that produces L-hydroxyproline directly from …
Structure-based engineering of minimal proline dehydrogenase domains for inhibitor discovery
Proline dehydrogenase (PRODH) catalyzes the FAD-dependent oxidation of l-proline to Δ1-
pyrroline-5-carboxylate and is a target for inhibitor discovery because of its importance in …
pyrroline-5-carboxylate and is a target for inhibitor discovery because of its importance in …
Structural basis for the stereospecific inhibition of the dual proline/hydroxyproline catabolic enzyme ALDH4A1 by trans‐4‐hydroxy‐L‐proline
Abstract Aldehyde dehydrogenase 4A1 (ALDH4A1) catalyzes the final steps of both proline
and hydroxyproline catabolism. It is a dual substrate enzyme that catalyzes the NAD+ …
and hydroxyproline catabolism. It is a dual substrate enzyme that catalyzes the NAD+ …