In the catheterization laboratory, the measurement of physiological indexes can help identify
functionally significant lesions and has become one of the standard methods to guide …

This Perspective article is a form of 'pastiche', inspired by the 1993 review by Lincoff and
Topol entitled 'Illusion of reperfusion', and explores how their concept continues to apply to …

Background The geographical disparity in the pathophysiological pattern of coronary artery
disease (CAD) among patients undergoing percutaneous coronary intervention (PCI) is …

Background Coronary angiography-derived radial wall strain (RWS) is a newly developed
index that can be readily accessed and describes the biomechanical features of a lesion …

Background Physiology-guided coronary revascularization was shown to improve clinical
outcomes in multiple patient subsets, whilst in those presenting with acute coronary …

The role of the local hemodynamic forces on plaque formation and destabilization was
recognized following the inception of the vulnerable plaque concept. 1 In the 1970s, Caro et …

Furthermore, the search and treatment of myocardial ischemia, which for years had been
supported as the most reliable strategy to improve patient prognosis, lost credibility. Even …

Background: Coronary biomechanical stress contributes to the plaque rupture and
subsequent events. This study aimed to investigate the impact of plaque biomechanical …

The coronary arteries experience altered hemodynamic and biomechanical conditions in the
presence of arterial plaque. Current coronary imaging techniques can determine the major …

Background Physiology-guided coronary revascularization was shown to improve clinical
outcomes in multiple patient subsets, whilst in those presenting with acute coronary …