Principles of odor coding in vertebrates and artificial chemosensory systems

I Manzini, D Schild, C Di Natale - Physiological reviews, 2022 - journals.physiology.org
The biological olfactory system is the sensory system responsible for the detection of the
chemical composition of the environment. Several attempts to mimic biological olfactory …

Modulation of olfactory signal detection in the olfactory epithelium: focus on the internal and external environment, and the emerging role of the immune system

B Bryche, C Baly, N Meunier - Cell and Tissue Research, 2021 - Springer
Detection and discrimination of odorants by the olfactory system plays a pivotal role in
animal survival. Olfactory-based behaviors must be adapted to an ever-changing …

Antagonistic odor interactions in olfactory sensory neurons are widespread in freely breathing mice

JD Zak, G Reddy, M Vergassola, VN Murthy - Nature communications, 2020 - nature.com
Odor landscapes contain complex blends of molecules that each activate unique,
overlapping populations of olfactory sensory neurons (OSNs). Despite the presence of …

Substance P and Prokineticin-2 are overexpressed in olfactory neurons and play differential roles in persons with persistent post-COVID-19 olfactory dysfunction

T Schirinzi, R Lattanzi, D Maftei, P Grillo… - Brain, Behavior, and …, 2023 - Elsevier
Persistent olfactory dysfunction (OD) is one of the most complaining and worrying
complications of long COVID-19 because of the potential long-term neurological …

Olfaction across the water–air interface in anuran amphibians

L Weiss, I Manzini, T Hassenklöver - Cell and Tissue Research, 2021 - Springer
Extant anuran amphibians originate from an evolutionary intersection eventually leading to
fully terrestrial tetrapods. In many ways, they have to deal with exposure to both terrestrial …

Molecular basis of mammalian odor discrimination: a status report

E Block - Journal of agricultural and Food Chemistry, 2018 - ACS Publications
Humans have 396 unique, intact olfactory receptors (ORs), G-protein coupled receptors
(GPCRs) containing receptor-specific binding sites; other mammals have more. Activation of …

Unravelling the olfactory sense: from the gene to odor perception

CS Silva Teixeira, NM Cerqueira… - Chemical …, 2016 - academic.oup.com
Although neglected by science for a long time, the olfactory sense is now the focus of a
panoply of studies that bring new insights and raises interesting questions regarding its …

Olfactory regulation by dopamine and DRD2 receptor in the nose

HQ Zhou, LJ Zhuang, HQ Bao, SJ Li… - Proceedings of the …, 2022 - National Acad Sciences
Olfactory behavior is important for animal survival, and olfactory dysfunction is a common
feature of several diseases. Despite the identification of neural circuits and circulating …

Testing links of food-related olfactory perception to peripheral ghrelin and leptin concentrations

R Ginieis, S Abeywickrema, I Oey, M Peng - Frontiers in Nutrition, 2022 - frontiersin.org
The peptide hormones ghrelin and leptin play major roles in the regulation of appetite and
food intake. However, the precise effects of these hormones on sensory processing remain a …

Sex steroid hormone synthesis, metabolism, and the effects on the mammalian olfactory system

T Abaffy, HY Lu, H Matsunami - Cell and tissue research, 2023 - Springer
Sex steroid hormones influence olfactory-mediated social behaviors, and it is generally
hypothesized that these effects result from circulating hormones and/or neurosteroids …