Majority of the human genome is transcribed to RNAs that do not encode proteins. These
non-coding RNAs (ncRNAs) play crucial roles in regulating the initiation and progression of …

MicroRNAs (miRNAs) are a type of small non-coding RNA molecule that performs an
important role in post‑transcriptional gene regulation. Since miRNAs were first identified in …

The effective and efficient management of cancer patients relies upon early diagnosis and/or
the monitoring of treatment, something that is often difficult to achieve using standard tissue …

Abstract Epstein–Barr virus (EBV), aetiologically linked to nasopharyngeal carcinoma
(NPC), is the first human virus found to encode many miRNAs. However, how these viral …

Stroke is the number one cause of neurological dysfunction in adults and has a heavy
socioeconomic burden worldwide. The etiological origins of ischemic stroke and resulting …

Type 1 diabetes mellitus (T1DM) is a disease where destruction of the insulin producing
pancreatic beta-cells leads to increased blood sugar levels. Both genetic and environmental …

The functional rules for microRNA (miRNA) targeting remain controversial despite their
biological importance because only a small fraction of distinct interactions, called site types …

Gastric cancer (GC) is the fourth most common type of cancer worldwide and
chemoresistance is a major obstacle to successful GC treatment. In the present study …

Accumulating data have shown the involvement of microRNAs in cancerous processes as
either oncogenes or tumor suppressor genes. Here, we established miR-30a as a tumor …

Purpose: To identify deregulated and inhibitory miRNAs and generate novel mimics for
replacement nanomedicine for head and neck squamous cell carcinomas (HNSCC) …