Plasma protein binding: from discovery to development

T Bohnert, LS Gan - Journal of pharmaceutical sciences, 2013 - Elsevier
The importance of plasma protein binding (PPB) in modulating the effective drug
concentration at pharmacological target sites has been the topic of significant discussion …

Consensus report on therapeutic drug monitoring of mycophenolic acid in solid organ transplantation

DRJ Kuypers, Y Le Meur, M Cantarovich… - Clinical journal of the …, 2010 - journals.lww.com
With the increasing use of mycophenolic acid (MPA) in solid organ transplantation, the need
for more accurate drug dosing has become evident. Personalized immunosuppressive …

The International Society for Heart and Lung Transplantation (ISHLT) guidelines for the care of heart transplant recipients

A Velleca, MA Shullo, K Dhital, E Azeka… - The Journal of Heart …, 2023 - jhltonline.org
Cochrane, Maria Crespo Leiro, Anne Dipchand, Brian Feingold, Kathleen Grady, Edward
Horn, Maryl Johnson, Donna Mancini, Sean Pinney, Heather Ross, Kari Wujcik, Andreas …

The International Society of Heart and Lung Transplantation Guidelines for the care of heart transplant recipients

MR Costanzo, A Dipchand, R Starling… - The Journal of heart and …, 2010 - Elsevier
CHAIR: Costanzo MR: Midwest Heart Foundation, Lombard Illinois, USA TASK FORCE 1:
Dipchand A: Hospital for Sick Children, Toronto Ontario, Canada; Starling R: Cleveland …

[PDF][PDF] Paediatric rheumatology

RE Petty - Egyptian Pharmaceutical Journal, 2012 - journals.ekb.eg
The last decade has witnessed rapid growth in awareness of the rheumatic diseases of
childhood, an enhanced understanding of many of the unique aspects of their presentation …

Pharmacology and toxicology of mycophenolate in organ transplant recipients: an update

CE Staatz, SE Tett - Archives of toxicology, 2014 - Springer
This review aims to provide an update of the literature on the pharmacology and toxicology
of mycophenolate in solid organ transplant recipients. Mycophenolate is now the …

High within-patient variability in the clearance of tacrolimus is a risk factor for poor long-term outcome after kidney transplantation

LCP Borra, JI Roodnat, JA Kal… - Nephrology Dialysis …, 2010 - academic.oup.com
Background. We hypothesized that a high within-patient variability in clearance of tacrolimus
and mycophenolate mofetil (MMF) would put patients at risk for periods of over-or …

Prevention of complications from use of conventional immunosuppressants: a critical review

C Ponticelli, RJ Glassock - Journal of nephrology, 2019 - Springer
Synthetic immunosuppressive drugs are largely used in immune-related renal diseases and
in kidney transplantation. Most of these drugs have a low therapeutic index (the ratio that …

Therapeutic drug monitoring of tacrolimus and mycophenolic acid in outpatient renal transplant recipients using a volumetric dried blood spot sampling device

TC Zwart, SRM Gokoel… - British journal of …, 2018 - Wiley Online Library
Aims Tacrolimus and mycophenolic acid dosing after renal transplantation is individualized
through therapeutic drug monitoring (TDM). Home‐based dried blood spot (DBS) sampling …

Severe COVID‐19 in a renal transplant recipient: a focus on pharmacokinetics

S Meziyerh, TC Zwart, RW van Etten… - American Journal of …, 2020 - Wiley Online Library
The current coronavirus disease 2019 (COVID‐19) pandemic requires extra attention for
immunocompromised patients, including solid organ transplant recipients. We report on a …