Bone is a hard yet dynamic tissue with remarkable healing capacities. Research to date has
greatly advanced the understanding of how bone heals and has led to marked success in …

Dental pulp stem cells (DPSCs) have a high capacity for differentiation and the ability to
regenerate a dentin/pulp-like complex. Numerous studies have provided evidence of …

APO‐1 (Fas/CD95), a member of the tumor necrosis factor receptor superfamily, induces
apoptosis upon receptor oligomerization. In a search to identify intracellular signaling …

Brain‐derived neurotrophic factor (BDNF) is a prototypic neurotrophin that regulates diverse
developmental events from the selection of neural progenitors to the terminal dendritic …

Alzheimer disease (AD) represents an oncoming epidemic that without an effective
treatment promises to exact extraordinary financial and emotional burdens. Studies of …

Cancer cells often develop resistance to chemotherapy or irradiation through mutations in
the p53 tumour-suppressor gene, which prevent apoptosis induction in response to cellular …

Brain-derived neurotrophic factor (BDNF), a member of the neurotrophin family, plays critical
roles in the survival, growth, and maintenance of brain and peripheral neurons. We report …

Mouse anti-Fas monoclonal antibody has a cytolytic activity on human cells that express the
antigen. Complementary DNAs encoding the cell surface antigen Fas were isolated from a …

Neurons are specialized cells with a complex morphology that represent the functional unit
of the nervous system. They are generated in remarkable numbers, particularly in higher …

The neurotrophins are growth factors that play critical roles in the development,
maintenance, survival, and death of the nervous system. The signal transducing systems …