[HTML][HTML] Lipid metabolism in MASLD and MASH: From mechanism to the clinic

F Carli, G Della Pepa, S Sabatini, AV Puig… - JHEP Reports, 2024 - Elsevier
Abstract Metabolic Associated-dysfunction Steatotic Liver Disease (MASLD) is recognized
as a metabolic disease characterized by excess intrahepatic lipid accumulation due to lipid …

Ursachen, Klinik und Folgen der Insulinresistenz bei Typ-2-Diabetes

G Xourafa, M Roden - Die Diabetologie, 2024 - Springer
Insulinresistenz beschreibt die verminderte Wirkung von Insulin an seinen Zielorganen und
ist einerseits ein physiologisches Phänomen wie bei Dehydratation oder Fieber …

Dioscin improves fatty liver hemorrhagic syndrome by promoting ERα-AMPK mediated mitophagy in laying hens

Y Xing, B Huang, Z Cui, Q Zhang, H Ma - Phytomedicine, 2024 - Elsevier
Background Mitochondria play a crucial role in upholding metabolic homeostasis.
Mitochondrial damage closely associated with the pathogenesis of fatty liver hemorrhagic …

Investigating the Role of Mitochondria in Metabolic Dysfunction Associated Steatohepatitis

J Nichols - 2024 - search.proquest.com
Metabolic dysfunction associated steatotic liver disease (MASLD) is a worldwide problem,
affecting more than 20% of the population. As poor diet and sedentary lifestyles become …

Identification of Mitophagy-Associated Genes for the Prediction of Metabolic Dysfunction-Associated Steatohepatitis Based on Interpretable Machine Learning Models

B Deng, Y Chen, P He, Y Liu, Y Li, Y Cai… - Journal of Inflammation …, 2024 - Taylor & Francis
Background This study aims to elucidate the role of mitochondrial autophagy in metabolic
dysfunction-associated steatohepatitis (MASH) by identifying and validating key mitophagy …