Neurodegenerative diseases are the most common cause of dementia. Although their
underlying molecular pathologies have been identified, there is substantial heterogeneity in …

The brain is a network of interleaved neural circuits. In modern connectomics, brain
connectivity is typically encoded as a network of nodes and edges, abstracting away the rich …

Isolated rapid eye movement sleep behaviour disorder (iRBD) is a sleep disorder
characterized by the loss of rapid eye movement sleep muscle atonia and the appearance of …

Parkinson's disease pathology is hypothesized to spread through the brain via axonal
connections between regions and is further modulated by local vulnerabilities within those …

Background Cervical dystonia (CD) is a form of isolated focal dystonia typically associated to
abnormal head, neck, and shoulder movements and postures. The complexity of the clinical …

Background Parkinson's disease (PD) patients suffer from progressive gray matter volume
(GMV) loss, but whether distinct patterns of atrophy progression exist within PD are still …

Background Peri-lead edema (PLE) is a poorly understood complication of deep brain
stimulation (DBS), which has been described in patients presenting occasionally with …

Amyotrophic Lateral Sclerosis (ALS) is a progressive neurodegenerative disease that
predominantly targets the motor system. Spread of pathology is thought to be driven by both …