Piperazine heterocycles as potential anticancer agents: A review
Cancer is a rapid, out of control, and proliferation pathology of ordinary cells, which has
become one of the most infamous and aggressive health afflictions worldwide. Molecular …
become one of the most infamous and aggressive health afflictions worldwide. Molecular …
New horizons in benzothiazole scaffold for cancer therapy: Advances in bioactivity, functionality, and chemistry
In the pasture of oncology, anticancer agents having advanced modes of action are of great
interest because of increasing chronicity of resistance against anticancer drugs. Heterocyclic …
interest because of increasing chronicity of resistance against anticancer drugs. Heterocyclic …
Synthetic and medicinal perspective of fused-thiazoles as anticancer agents
Background: Cancer is second leading disease after cardiovascular disease. Presently,
Chemotherapy, Radiotherapy and use of chemicals are some treatments available these …
Chemotherapy, Radiotherapy and use of chemicals are some treatments available these …
Quinoline-and Isoindoline-Integrated Polycyclic Compounds as Antioxidant, and Antidiabetic Agents Targeting the Dual Inhibition of α-Glycosidase and α-Amylase …
M Al-Ghorbani, O Alharbi, AB Al-Odayni, NAY Abduh - Pharmaceuticals, 2023 - mdpi.com
Novel analogs of quinoline and isoindoline containing various heterocycles, such as
tetrazole, triazole, pyrazole, and pyridine, were synthesized and characterized using FT-IR …
tetrazole, triazole, pyrazole, and pyridine, were synthesized and characterized using FT-IR …
An insight into the therapeutic potential of piperazine-based anticancer agents
K Walayat, NULA MOHSIN, S Aslam… - Turkish Journal of …, 2019 - journals.tubitak.gov.tr
The piperazine ring system is among the medicinally important nitrogen-containing
heterocyclic ring systems and is exploited for the synthesis of various drug molecules. A …
heterocyclic ring systems and is exploited for the synthesis of various drug molecules. A …
Synthesis and docking studies of pyrazole-benzamide-benzothiazole conjugates as xanthine oxidase inhibitor candidates
NK MJ, R Ramu, M Al-Ghorbani, SA Khanum - Journal of Molecular …, 2023 - Elsevier
A series of benzothiazole bearing pyrazole derivatives (6a-j) were synthesized via
mechanochemical synthesis through hand grinding using pestle and mortar, and their …
mechanochemical synthesis through hand grinding using pestle and mortar, and their …
A novel, rapid and eco-sustainable approach for the synthesis of novel benzothiazole derivatives as potent urease inhibitors: biological assay, molecular docking …
Recently, benzothiazole derivatives have garnered significant attention among the research
community due to their pharmaceutical and biological significance. Likewise, in this study …
community due to their pharmaceutical and biological significance. Likewise, in this study …
Thiazole, isatin and phthalimide derivatives tested in vivo against cancer models: a literature review of the last six years
AF Pinto, JS Nunes, JE Severino Martins… - Current Medicinal …, 2024 - ingentaconnect.com
Background: Cancer is a disease characterized by the abnormal multiplication of cells and is
the second leading cause of death in the world. The search for new effective and safe …
the second leading cause of death in the world. The search for new effective and safe …
Pyridine-1,3,4-Thiadiazole-Schiff Base Derivatives, as Antioxidant and Antimitotic Agent: Synthesis and in Silico ADME Studies
AA Pund, MH Shaikh, BG Chandak… - Polycyclic Aromatic …, 2023 - Taylor & Francis
An efficient method developed for the synthesis of asymmetric (S)-N-benzylidene-2-
(benzyloxy)-1-(5-(pyridin-2-yl)-1, 3, 4-thiadiazol-2-yl) ethanamine derivatives with excellent …
(benzyloxy)-1-(5-(pyridin-2-yl)-1, 3, 4-thiadiazol-2-yl) ethanamine derivatives with excellent …
Spectroscopic (FT-IR, FT-Raman, UV, NMR, NLO) investigation, molecular docking and molecular simulation dynamics on 1-Methyl-3-Phenylpiperazine
K Subashini, S Periandy - Journal of Molecular Structure, 2017 - Elsevier
The title compound was analyzed, by recording FT-IR (4000-400 cm− 1) and FT-Raman
(4000-100 cm− 1) spectra in solid phase, 1 H and 13 C NMR in CDCl 3 (deuterated …
(4000-100 cm− 1) spectra in solid phase, 1 H and 13 C NMR in CDCl 3 (deuterated …