Overview of paratransgenesis as a strategy to control pathogen transmission by insect vectors

NA Ratcliffe, JP Furtado Pacheco, P Dyson… - Parasites & vectors, 2022 - Springer
This article presents an overview of paratransgenesis as a strategy to control pathogen
transmission by insect vectors. It first briefly summarises some of the disease-causing …

Increasing dengue burden and severe dengue risk in Bangladesh: an overview

MEH Kayesh, I Khalil, M Kohara… - Tropical Medicine and …, 2023 - mdpi.com
Dengue is a prevalent and rapidly spreading mosquito-borne viral disease affecting
humans. The geographic range of dengue is expanding, and much like in many other …

Efficacy of Wolbachia-infected mosquito deployments for the control of dengue

A Utarini, C Indriani, RA Ahmad… - … England Journal of …, 2021 - Mass Medical Soc
Background Aedes aegypti mosquitoes infected with the w Mel strain of Wolbachia pipientis
are less susceptible than wild-type A. aegypti to dengue virus infection. Methods We …

Efficient production of male Wolbachia-infected Aedes aegypti mosquitoes enables large-scale suppression of wild populations

JE Crawford, DW Clarke, V Criswell, M Desnoyer… - Nature …, 2020 - nature.com
The range of the mosquito Aedes aegypti continues to expand, putting more than two billion
people at risk of arboviral infection. The sterile insect technique (SIT) has been used to …

Symbionts and gene drive: two strategies to combat vector-borne disease

GH Wang, J Du, CY Chu, M Madhav, GL Hughes… - Trends in Genetics, 2022 - cell.com
Mosquitoes bring global health problems by transmitting parasites and viruses such as
malaria and dengue. Unfortunately, current insecticide-based control strategies are only …

Mosquito trilogy: microbiota, immunity and pathogens, and their implications for the control of disease transmission

P Gabrieli, S Caccia, I Varotto-Boccazzi… - Frontiers in …, 2021 - frontiersin.org
In mosquitoes, the interaction between the gut microbiota, the immune system, and the
pathogens that these insects transmit to humans and animals is regarded as a key …

Stable high-density and maternally inherited Wolbachia infections in Anopheles moucheti and Anopheles demeilloni mosquitoes

T Walker, S Quek, CL Jeffries, J Bandibabone… - Current Biology, 2021 - cell.com
Wolbachia, a widespread bacterium that can reduce pathogen transmission in mosquitoes,
has recently been reported to be present in Anopheles (An.) species. In wild populations of …

Transgenic expression of cif genes from Wolbachia strain wAlbB recapitulates cytoplasmic incompatibility in Aedes aegypti

CJ McNamara, TH Ant, T Harvey-Samuel… - Nature …, 2024 - nature.com
The endosymbiotic bacteria Wolbachia can invade insect populations by modifying host
reproduction through cytoplasmic incompatibility (CI), an effect that results in embryonic …

Systematic Review of Wolbachia Symbiont Detection in Mosquitoes: An Entangled Topic about Methodological Power and True Symbiosis

LM Inacio da Silva, FZ Dezordi, MHS Paiva, GL Wallau - Pathogens, 2021 - mdpi.com
Wolbachia is an endosymbiotic bacterium that naturally infects several arthropods and
nematode species. Wolbachia gained particular attention due to its impact on their host …

Wolbachia's Deleterious Impact on Aedes aegypti Egg Development: The Potential Role of Nutritional Parasitism

MJ Allman, JE Fraser, SA Ritchie, DA Joubert… - Insects, 2020 - mdpi.com
Simple Summary Mosquito-borne viral diseases such as dengue, Zika and chikungunya
cause a significant global health burden and are currently increasing in outbreak frequency …