Primary brain tumours in adults

MJ van den Bent, M Geurts, PJ French, M Smits… - The Lancet, 2023 - thelancet.com
The most frequent adult-type primary CNS tumours are diffuse gliomas, but a large variety of
rarer CNS tumour types exists. The classification of these tumours is increasingly based on …

Isocitrate dehydrogenase (IDH) mutant gliomas: a Society for Neuro-Oncology (SNO) consensus review on diagnosis, management, and future directions

JJ Miller, LN Gonzalez Castro, S McBrayer… - Neuro …, 2023 - academic.oup.com
Isocitrate dehydrogenase (IDH) mutant gliomas are the most common adult, malignant
primary brain tumors diagnosed in patients younger than 50, constituting an important cause …

Interactive effects of molecular, therapeutic, and patient factors on outcome of diffuse low-grade glioma

SL Hervey-Jumper, Y Zhang, JJ Phillips… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE In patients with diffuse low-grade glioma (LGG), the extent of surgical tumor
resection (EOR) has a controversial role, in part because a randomized clinical trial with …

The oncological role of resection in newly diagnosed diffuse adult-type glioma defined by the WHO 2021 classification: a review by the RANO resect group

P Karschnia, JKW Gerritsen, N Teske, DP Cahill… - The Lancet …, 2024 - thelancet.com
Glioma resection is associated with prolonged survival, but neuro-oncological trials have
frequently refrained from quantifying the extent of resection. The Response Assessment in …

[HTML][HTML] Clinical management and survival outcomes of patients with different molecular subtypes of diffuse gliomas in China (2011–2017): a multicenter retrospective …

K Zhang, X Liu, G Li, X Chang, S Li, J Chen… - Cancer biology & …, 2022 - ncbi.nlm.nih.gov
Objective: We aimed to summarize the clinicopathological characteristics and prognostic
features of various molecular subtypes of diffuse gliomas (DGs) in the Chinese population …

Glioma biopsies Classification Using Raman Spectroscopy and Machine Learning Models on Fresh Tissue Samples

M Riva, T Sciortino, R Secoli, E D'Amico, S Moccia… - Cancers, 2021 - mdpi.com
Simple Summary Raman Spectroscopy (RS) is an optical technique able to determine
biochemical differences within a biological tissue, yet there are few reports of its application …

Long-term autonomy, professional activities, cognition, and overall survival after awake functional-based surgery in patients with IDH-mutant grade 2 gliomas: a …

S Ng, V Rigau, S Moritz-Gasser, C Gozé… - The Lancet Regional …, 2024 - thelancet.com
Background In isocitrate dehydrogenase (IDH)-mutant low-grade gliomas (LGGs), awake
functional-based resection (ie, resection based on intraoperative functional responses rather …

Raman spectroscopy and machine learning for IDH genotyping of unprocessed glioma biopsies

T Sciortino, R Secoli, E d'Amico, S Moccia… - Cancers, 2021 - mdpi.com
Simple Summary Isocitrate dehydrogenase (IDH) mutation is one of the most important
prognostic markers in glioma tumors. Raman spectroscopy (RS) is an optical technique with …

The benefit of early surgery on overall survival in incidental low-grade glioma patients: A multicenter study

T Ius, S Ng, JS Young, B Tomasino, M Polano… - Neuro …, 2022 - academic.oup.com
Background The role of surgery for incidentally discovered diffuse incidental low-grade
gliomas (iLGGs) is debatable and poorly documented in current literature. Objective The aim …

Multivariate mapping of low-resilient neurocognitive systems within and around low-grade gliomas

S Ng, S Moritz-Gasser, AL Lemaitre, H Duffau… - Brain, 2024 - academic.oup.com
Accumulating evidence suggests that the brain exhibits a remarkable capacity for functional
compensation in response to neurological damage, a resilience potential that is deeply …