Naturally occurring canine cancers have remarkable similarities to their human counterparts.
To better understand these similarities, we investigated 671 client-owned dogs from 96 …

Clinical care of osteosarcoma (OSA) in companion dogs has been relatively static during the
past 20 years. The disease of OSA can be described as one of “life and limb.” The limb pain …

Dogs are humanity's oldest friend, the first species we domesticated 20,000–40,000 years
ago. In this unequaled collaboration, dogs have inadvertently but serendipitously been …

Canine osteosarcoma is increasingly recognized as an informative model for human
osteosarcoma. Here we show in one of the largest clinically annotated canine osteosarcoma …

Background Growing evidence from dogs and humans supports the abundance of mutation‐
based biomarkers in tumors of dogs. Increasing the use of clinical genomic diagnostic …

Osteosarcoma is a highly metastatic primary bone tumour that occurs spontaneously in both
pet dogs and humans. Patterns of metastasis to organs beyond the most common site (lung) …

The characterization of immortalized canine osteosarcoma (OS) cell lines used for research
has historically been based on phenotypic features such as cellular morphology and …

Simple Summary This research aims to address the significant knowledge gap regarding
microsatellite instability (MSI) in canine cancers. While MSI has been extensively studied in …

Osteosarcoma (OS) is the most common malignant bone tumor in children and adolescents.
It is characterized by a rapid progression, poor prognosis, and early pulmonary metastasis …

Cancer is a leading cause of non-communicable morbidity and mortality throughout the
world, similarly, in dogs, the most frequent cause of mortality is tumors. Some types of …