Statins were first identified over 40 years ago as lipid-lowering drugs and have been remarkably effective in treating cardiovascular diseases. As research advanced, the …
GJ Wijnant, F Dumetz, L Dirkx, D Bulté… - Frontiers in Tropical …, 2022 - frontiersin.org
Leishmaniasis is a tropical infectious disease caused by the protozoan Leishmania parasite. The disease is transmitted by female sand flies and, depending on the infecting parasite …
Leishmaniasis is a vector-borne neglected tropical disease caused by protozoan parasites of the genus Leishmania for which there is a paucity of effective viable non-toxic drugs …
MD Ngo, S Bartlett, K Ronacher - Microorganisms, 2021 - mdpi.com
Diabetes is a major risk factor for tuberculosis (TB). Diabetes increases the risk of the progression from latent tuberculosis infection (LTBI) to active pulmonary TB and TB patients …
A Sheridan, CPD Wheeler-Jones, MC Gage - Immuno, 2022 - mdpi.com
Statins are 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors used worldwide to manage dyslipidaemia and thus limit the development of atherosclerotic …
S Varikuti, BK Jha, G Volpedo, NM Ryan… - Frontiers in …, 2018 - frontiersin.org
The neglected tropical diseases (NTDs) caused by protozoan parasites are responsible for significant morbidity and mortality worldwide. Current treatments using anti-parasitic drugs …
CAB Nieva, AG Cid, AI Romero, MF García-Bustos… - Acta Tropica, 2021 - Elsevier
Abstract Leishmaniasis is a Neglected Tropical Diseases caused by protozoan parasites of the genus Leishmania. It is a major health problem in many tropical and subtropical regions …
S Hendrickx, G Caljon, L Maes - Parasitology research, 2019 - Springer
Leishmaniasis is a neglected parasitic disease for which the current antileishmania therapeutics are hampered by drug toxicity, high cost, need for parenteral administration …
Methods A literature search using keywords “statin” or “statins” combined with “minimum inhibitory concentration”(MIC) was performed in six databases on 7th April 2017. After …