Promise and pitfalls of g-ratio estimation with MRI

JSW Campbell, IR Leppert, S Narayanan, M Boudreau… - Neuroimage, 2018 - Elsevier
The fiber g-ratio is the ratio of the inner to the outer diameter of the myelin sheath of a
myelinated axon. It has a limited dynamic range in healthy white matter, as it is optimized for …

Diffusion‐relaxation correlation spectroscopic imaging: a multidimensional approach for probing microstructure

D Kim, EK Doyle, JL Wisnowski… - Magnetic resonance …, 2017 - Wiley Online Library
Purpose To propose and evaluate a novel multidimensional approach for imaging subvoxel
tissue compartments called Diffusion‐Relaxation Correlation Spectroscopic Imaging. Theory …

Multidimensional correlation spectroscopic imaging of exponential decays: from theoretical principles to in vivo human applications

D Kim, JL Wisnowski, CT Nguyen… - NMR in …, 2020 - Wiley Online Library
Multiexponential modeling of relaxation or diffusion MR signal decays is a popular approach
for estimating and spatially mapping different microstructural tissue compartments. While this …

Disentangling in two dimensions in the living human brain: Feasbilty of relaxometry-diffusometry using ultra-strong gradients

C Tax, U Rudrapatna, T Witzel… - Proc Intl Soc Mag Reson …, 2017 - archive.ismrm.org
Combining multiple, complementary contrasts into one analysis will yield deeper
understanding of white matter physiology than using diffusion MRI (dMRI) alone. Varying TE …

[PDF][PDF] Faster diffusion-relaxation correlation spectroscopic imaging (DR-CSI) using optimized experiment design

D Kim, JP Haldar - Proc. Int. Soc. Magn. Reson. Med, 2017 - mr.usc.edu
We propose a new experiment design method to accelerate the recent novel diffusion-
relaxation correlation spectroscopic imaging (DRCSI) experiment. DR-CSI acquires imaging …

[PDF][PDF] Tissue microstructure characterisation through relaxometry and diffusion MRI using sparse component analysis

M Molina-Romero, PA Gómez, JI Sperl… - … on Breaking the …, 2016 - campar.in.tum.de
We introduce a new approach to characterise brain tissue microstructure combining
diffusion MRI and relaxometry. The tissue is modelled as a composition of water pools with …

[PDF][PDF] Theory, validation and application of blind source separation to diffusion MRI for tissue characterisation and partial volume correction

M Molina-Romero, PA Gómez, JI Sperl… - Proceedings of the …, 2017 - campar.in.tum.de
Here we present blind source separation (BSS) as a new tool to analyse multi-echo diffusion
data. This technique is designed to separate mixed signals and is widely used in audio and …

T2 relaxation rates of the fast and slow bi-exponential diffusion components in the in vivo corpus callosum

Q Fan, SY Huang, A Nummenmaa, T Witzel, LL Wald - archive.ismrm.org
Bi-exponential diffusion model is widely used to fit for non-Gaussian diffusion. T2 relaxation
rates differ between structural compartments, which may bias the results of fits to …

[PDF][PDF] Phantom Validation of Diffusion-Relaxation Correlation Spectroscopic Imaging (DR-CSI)

Diffusion-relaxation correlation spectroscopic imaging (DR-CSI) is a novel multidimensional
MR imaging approach that infers microscopic tissue compartments using simultaneous …