Major advances in biomedical imaging have occurred over the last 2 decades and now
allow many physiological, cellular, and molecular processes to be imaged noninvasively in …

Atherosclerosis is an inflammatory disease of large and medium-sized arteries,
characterized by the growth of atherosclerotic lesions (plaques). These plaques often …

Aims Mammalian models have been instrumental in investigating adult heart function and
human disease. However, electrophysiological differences with human hearts and high …

Atherosclerosis is a dynamic process starting with endothelial dysfunction and inflammation
and eventually leading to life-threatening arterial plaques. Exercise generally improves …

Aortic valve stenosis (AS) is the most frequent valve disease with relevant prognostic impact.
Experimental model systems for AS are scarce and comprehensive imaging techniques to …

MRI sensitivity for diagnosis and localization of early myocarditis is limited, although it is of
central clinical interest. The aim of this project was to test a contrast agent targeting activated …

Preclinical 4D flow MRI remains challenging and is restricted for parallel imaging
acceleration due to the limited number of available receive channels. A radial acquisition …

Purpose Wall shear stress (WSS) and pulse wave velocity (PWV) are important parameters
to characterize blood flow in the vessel wall. Their quantification with flow-sensitive phase …

Purpose 4D flow cardiovascular magnetic resonance (CMR) and the assessment of wall
shear stress (WSS) are non-invasive tools to study cardiovascular risks in vivo. Major …

Type 1 diabetes is a chronic autoimmune disease that affects tens of millions of people.
Diabetes mellitus is one of the strongest factors in the development of cerebrovascular …