In recent years, chronic overnutrition, such as consumption of a high-fat diet (HFD), has
been increasingly viewed as a significant modifiable risk factor for diseases such as …

Adenosine receptors (ARs) function in the body's response to conditions of pathology and
stress associated with a functional imbalance, such as in the supply and demand of …

Queens and workers of eusocial Hymenoptera are considered homologous to the
reproductive and brood care phases of an ancestral subsocial life cycle. However, the …

Adenosine is a key extracellular signalling molecule that regulates several aspects of tissue
function by activating four G-protein-coupled receptors, A1, A2A, A2B and A1 adenosine …

Adenosine is an endogenous ubiquitous purine nucleoside, which is increased by hypoxia,
ischaemia and tissue damage and mediates a number of physiopathological effects by …

Extracellular adenosine is a ubiquitous signaling molecule that modulates a wide array of
biological processes. Recently, significant advances have been made in our understanding …

Extracellular nucleosides and nucleotides, such as adenosine and adenosine triphosphate
(ATP), are involved in many physiological and pathological processes in adipose tissue …

Adenosine has broad activities in organisms due to the existence of multiple receptors, the
differential adenosine concentrations necessary to activate these receptors and the …

Adenosine as well as agonists and antagonists for the four adenosine receptor subtypes
(A1R, A2AR, A2BR and A3R) play a role in several key physiological and …

Purine nucleotides and nucleosides are involved in various human physiological and
pathological mechanisms. The pathological deregulation of purinergic signaling contributes …