The unicellular protozoan parasites of the genus Plasmodium impose on human health
worldwide the enormous burden of malaria. The possibility to genetically modify several …

The complicated life cycle of the malaria parasite involves a vertebrate host and a mosquito
vector, and translational regulation plays a prominent role in orchestrating the …

Underlying the development of malaria parasites within erythrocytes and the resulting
pathogenicity is a hardwired program that secures proper timing of gene transcription and …

Background In eukaryotic organisms, gene expression is regulated at multiple levels during
the processes of transcription and translation. The absence of a tight regulatory network for …

Among components of the translational machinery, ribonucleoside modifications on tRNA s
are emerging as critical regulators of cell physiology and stress response. Here, we …

Translational control regulates the levels of protein synthesized from its transcript and is key
for the rapid adjustment of gene expression in response to environmental stimuli. The …

Clonally variant protein expression in the malaria parasite Plasmodium falciparum
generates phenotypic variability and allows isogenic populations to adapt to environmental …

Ribonucleoside modifications comprising the epitranscriptome are present in all organisms
and all forms of RNA, including mRNA, rRNA and tRNA, the three major RNA components of …

Plasmodium ovale accounts for a disproportionate number of travel-related malaria cases.
This parasite is understudied since there is a reliance on clinical samples. We collected a P …

Eukaryotic, unicellular parasites of the Plasmodium genus are the causative agents of
malaria. During their life cycle, these parasites alternate between a vertebrate and an insect …