Signaling pathways governing breast cancer stem cells behavior

K Song, M Farzaneh - Stem Cell Research & Therapy, 2021 - Springer
Breast cancer is the second common cancer and the leading cause of malignancy among
females overall. Breast cancer stem cells (BCSCs) are a small population of breast cancer …

Targeting cancer stem cells as the key driver of carcinogenesis and therapeutic resistance

RA Eid, M Alaa Edeen, EM Shedid, ASS Kamal… - International Journal of …, 2023 - mdpi.com
The emerging concept of cancer stem cells (CSCs) as the key driver behind carcinogenesis,
progression, and diversity has displaced the prior model of a tumor composed of cells with …

Direct Assembly of Metal‐Phenolic Network Nanoparticles for Biomedical Applications

W Xu, Z Lin, S Pan, J Chen, T Wang… - Angewandte …, 2023 - Wiley Online Library
Coordination assembly offers a versatile means to developing advanced materials for
various applications. However, current strategies for assembling metal‐organic networks …

[HTML][HTML] Breast cancers, mammary stem cells, and cancer stem cells, characteristics, and hypotheses

S Taurin, H Alkhalifa - Neoplasia, 2020 - Elsevier
The cellular heterogeneity of breast cancers still represents a major therapeutic challenge.
The latest genomic studies have classified breast cancers in distinct clusters to inform the …

Tumor microenvironment-responsive nanohybrid for hypoxia amelioration with photodynamic and near-infrared II photothermal combination therapy

P Zhang, Q Wu, J Yang, M Hou, B Zheng, J Xu, Y Chai… - Acta Biomaterialia, 2022 - Elsevier
Phototherapy, particularly photothermal therapy (PTT) and photodynamic therapy (PDT), has
been widely investigated for tumor treatment. However, the limited tissue penetration depth …

The role of breast cancer stem cells in chemoresistance and metastasis in triple-negative breast cancer

L He, N Wick, SK Germans, Y Peng - Cancers, 2021 - mdpi.com
Simple Summary Triple negative breast cancer lacks targeted therapies and has poor
prognosis; chemotherapy is currently the main treatment modality. Growing evidence has …

[HTML][HTML] Cancer stem cells and macrophages: Molecular connections and future perspectives against cancer

B Aramini, V Masciale, G Grisendi, F Banchelli… - Oncotarget, 2021 - ncbi.nlm.nih.gov
Cancer stem cells (CSCs) have been considered the key drivers of cancer initiation and
progression due to their unlimited self-renewal capacity and their ability to induce tumor …

[HTML][HTML] Red blood cell-derived materials for cancer therapy: construction, distribution, and applications

J Ding, X Ding, W Liao, Z Lu - Materials Today Bio, 2024 - Elsevier
Cancer has become an increasingly important public health issue owing to its high morbidity
and mortality rates. Although traditional treatment methods are relatively effective, they have …

MiRNA-146a/AKT/β-catenin activation regulates cancer stem cell phenotype in oral squamous cell carcinoma by targeting CD24

S Ghuwalewala, D Ghatak, S Das, S Roy, P Das… - Frontiers in …, 2021 - frontiersin.org
CD44highCD24low population has been previously reported as cancer stem cells (CSCs) in
Oral Squamous Cell Carcinoma (OSCC). Increasing evidence suggests potential …

Fabrication and evaluation of a dual-targeting nanoparticle mediated CRISPR/Cas9 delivery to combat drug resistance in breast cancer cells

N Tavazohi, M Mirian, J Varshosaz… - Journal of Drug Delivery …, 2023 - Elsevier
Breast cancer treatment is hampered by drug resistance which leads to recurrence and
metastasis. Alteration of specific gene expression such as ERCC1 evidently acquires drug …