Ischemic stroke caused by arterial occlusion is the most common type of stroke, which is
among the most frequent causes of disability and death worldwide. Current treatment …

Macroautophagy is an evolutionarily conserved process that delivers diverse cellular
contents to lysosomes for degradation. As our understanding of this pathway grows, so does …

Autophagy is a self-eating cellular catabolic pathway, through which long-lived proteins,
damaged organelles and misfolded proteins are degraded and recycled for the …

Over 30 million people suffer from the consequences of ischemic stroke. The precise
molecular mechanism of neuronal damage during ischemic stroke remains unclear; …

The interaction of coagulation factors with the perivascular environment affects the
development of disease in ways that extend beyond their traditional roles in the acute …

(Macro) autophagy is a bulk degradation process that mediates the clearance of long-lived
proteins and organelles. Autophagy is initiated by double-membraned structures, which …

Ferroptosis is mechanism for non-apoptotic, iron-dependent, oxidative cell death that is
characterized by glutathione consumption and lipid peroxides accumulation. Ferroptosis is …

Cerebral ischemia-reperfusion (IR) is a complex pathological process. Although autophagy
can be evoked by ischemia, its involvement in the reperfusion phase after ischemia and its …

Autophagy is an intracellular degradation system that delivers cytoplasmic constituents to
the lysosome. Despite its simplicity, recent progress has demonstrated that autophagy plays …

Oxidative stress occurs in a variety of disease settings and is strongly linked to the
development of neuron death and neuronal dysfunction. Cells are equipped with numerous …