Cancer ranks among the top causes of mortality on a global scale. The only treatments available for cancer nowadays are surgery, radiation therapy, and the use of cytotoxic …
J Bonelli, E Ortega-Forte, G Vigueras… - … Applied Materials & …, 2024 - ACS Publications
Despite the potential of photodynamic therapy (PDT) in cancer treatment, the development of efficient and photostable photosensitizing molecules that operate at long wavelengths of …
MD Pozza, P Mesdom, A Abdullrahman… - Inorganic …, 2023 - ACS Publications
Lack of selectivity is one of the main issues with currently used chemotherapies, causing damage not only to altered cells but also to healthy cells. Over the last decades …
L Bretin, Y Husiev, V Ramu, L Zhang… - Angewandte Chemie …, 2024 - Wiley Online Library
Photoactivated chemotherapy (PACT) is a promising cancer treatment modality that kills cancer cells via photochemical uncaging of a cytotoxic drug. Most ruthenium‐based …
Ru (II) polypyridyl complexes have gained widespread attention as photosensitizers for photodynamic therapy (PDT). Herein, we systematically investigate a series of the type [Ru …
Z Zhao, J Li, W Yuan, D Cheng, S Ma… - Journal of the …, 2023 - ACS Publications
The emerging field of photoredox catalysis in mammalian cells enables spatiotemporal regulation of a wealth of biological processes. However, the selective cleavage of stable …
X Wang, J Peng, C Meng, F Feng - Chemical Science, 2024 - pubs.rsc.org
Photodynamic therapy (PDT) has been developed as a potential cancer treatment approach owing to its non-invasiveness, spatiotemporal control and limited side effects. Currently …
S Abyar, L Huang, Y Husiev, L Bretin… - Journal of Medicinal …, 2024 - ACS Publications
Photoactivated chemotherapy agents form a new branch of physically targeted anticancer agents with potentially lower systemic side effects for patients. On the other hand, limited …
Cross-linking strategies have found wide applications in chemical biology, enabling the labeling of biomolecules and monitoring of protein–protein interactions. Nitrone exhibits …