Single-cell transcriptomics has broadened our understanding of cellular diversity and gene
expression dynamics in healthy and diseased tissues. Recently, spatial transcriptomics has …

The extracellular matrix (ECM) of solid tumors impacts the antitumor activities of CD8+ T and
natural killer (NK) cells in a variety of ways. Cell motility is restricted by the tumor ECM which …

Spatial transcriptomics (ST) methods unlock molecular mechanisms underlying tissue
development, homeostasis, or disease. However, there is a need for easy-to-use, high …

Spatial transcriptomic profiling of cancer has enabled spatial delineation of malignant
transcriptional heterogeneity, intercellular communication, and organization of …

Endometrial cancer (EC) is a highly heterogeneous malignancy characterized by varied
pathology and prognoses, and the heterogeneity of its cancer cells and the tumor …

There is a pressing need to improve risk stratification and treatment selection for HPV-
negative head and neck squamous cell carcinoma (HNSCC) due to the adverse side effects …

Early and prompt reperfusion therapy has markedly improved the survival rates among
patients enduring myocardial infarction (MI). Nonetheless, the resulting adverse remodeling …

Hepatocellular carcinoma (HCC) is a leading contributor to cancer-related deaths worldwide
and presents significant challenges in diagnosis and treatment due to its heterogeneous …

Disulfidptosis is a recently identified mode of regulated cell death. Regulating disulfidptosis
in carcinoma is a promising therapeutic approach. Long non-coding RNAs (lncRNAs) have …

Many solid tumors exhibit significant genetic, cellular, and biophysical heterogeneity which
dynamically evolves during disease progression and after treatment. This constant flux in …