The use of amorphous solid dispersions is an interesting strategy to increase the
bioavailability of poorly soluble drugs by improving their rate and extent of dissolution. Lack …

The recent impact of the Biopharmaceutics Classification System (BCS) and the
Biopharmaceutics Drug Disposition Classification System (BDDCS) on relevant scientific …

Localization and tracking of ingestible microdevices in the gastrointestinal (GI) tract is
valuable for the diagnosis and treatment of GI disorders. Such systems require a large field …

The rate and extent of drug dissolution and absorption from solid oral dosage forms is highly
dependent upon the volumes and distribution of gastric and small intestinal water. However …

Abstract The Biopharmaceutics Classification System (BCS) has found widespread utility in
drug discovery, product development and drug product regulatory sciences. The …

Pharmaceutical solid oral dosage forms must undergo dissolution in the intestinal fluids of
the gastrointestinal tract before they can be absorbed and reach the systemic circulation …

Purpose The aim of this study was to update the compositions of biorelevant media to
represent the composition and physical chemical characteristics of the gastrointestinal fluids …

Lipid-based delivery systems are finding increasing application in the oral delivery of poorly
water-soluble, lipophilic drugs. Whilst lipidic dose forms may improve oral bioavailability via …

A revised classification system for oral drugs was developed using the biopharmaceutics
classification system (BCS) as a starting point. The revised system is designed to have a …

Written at a level comprehensible to non-experts, this handbook covers the current state of
encapsulation and controlled released technologies, presenting the fundamental processes …