Significance of interleukin (IL)-4 and IL-13 in inflammatory arthritis

M Iwaszko, S Biały, K Bogunia-Kubik - Cells, 2021 - mdpi.com
Interleukin (IL)-4 and IL-13 belong to the T helper 2 (Th2) cytokine family, along with IL-3, IL-
5, and IL-9. These cytokines are key mediators of allergic inflammation. They have important …

Mechanisms of disease: angiogenesis in inflammatory diseases

Z Szekanecz, AE Koch - Nature clinical practice Rheumatology, 2007 - nature.com
Angiogenesis, the development of new vessels, is an important process in health and
disease. The perpetuation of neovascularization in inflammatory diseases, such as …

Anti-angiogenic effect of Shikonin in rheumatoid arthritis by downregulating PI3K/AKT and MAPKs signaling pathways

C Liu, L He, J Wang, Q Wang, C Sun, Y Li, K Jia… - Journal of …, 2020 - Elsevier
Ethnopharmacological relevance Zicao is the dried root of Lithospermum erythrorhizon Sieb,
et Zucc, Arnebia euchroma (Royle) Johnst, or Arnebia guttata Bunge and commonly used to …

Interleukin-18: a mediator of inflammation and angiogenesis in rheumatoid arthritis

MV Volin, AE Koch - Journal of Interferon & Cytokine Research, 2011 - liebertpub.com
Interleukin-18 (IL-18) is a highly regulated inflammatory cytokine that is elevated in synovial
tissues and synovial fluids of patients with rheumatoid arthritis (RA) compared with patients …

Interleukin-18: a regulator of cancer and autoimmune diseases

M Esmailbeig, A Ghaderi - European cytokine network, 2017 - Springer
Abstract Interleukin (IL)-18, structurally similar to IL-1-, is a member of IL-1 superfamily of
cytokines. This cytokine, which is expressed by many human lymphoid and nonlymphoid …

Tumor angiogenesis: insights and innovations

F Nussenbaum, IM Herman - Journal of oncology, 2010 - Wiley Online Library
Angiogenesis is a vital process resulting in the formation of new blood vessels. It is normally
a highly regulated process that occurs during human development, reproduction, and …

Angiogenesis in rheumatoid arthritis

Z Szekanecz, T Besenyei, G Paragh, AE Koch - Autoimmunity, 2009 - Taylor & Francis
Angiogenesis is the formation of new capillaries from pre-existing vessels. A number of
soluble and cell-bound factors may stimulate neovascularization. The perpetuation of …

[HTML][HTML] IL-4 alone and in combination with IL-10 protects against blood-induced cartilage damage

MER van Meegeren, G Roosendaal… - Osteoarthritis and …, 2012 - Elsevier
OBJECTIVE: It has been reported that interleukin (IL)-10 limits blood-induced cartilage
damage. Our aim was to study the effect of IL-4 alone and in combination with IL-10 on …

Resolution of TLR2-induced inflammation through manipulation of metabolic pathways in rheumatoid arthritis

T McGarry, M Biniecka, W Gao, D Cluxton… - Scientific reports, 2017 - nature.com
During inflammation, immune cells activated by toll-like receptors (TLRs) have the ability to
undergo a bioenergetic switch towards glycolysis in a manner similar to that observed in …

The aortic ring model of angiogenesis: a quarter century of search and discovery

RF Nicosia - Journal of cellular and molecular medicine, 2009 - Wiley Online Library
Introduction‐Early history of the aortic ring model‐Morphology of the angiogenic response‐
Source of microvessels in aortic cultures‐Stimulatory effect of angiogenesis on cancer …