The role of antioxidants and antioxidant-related enzymes in protective responses to environmentally induced oxidative stress

J Limón-Pacheco, ME Gonsebatt - Mutation Research/Genetic Toxicology …, 2009 - Elsevier
In aerobic organisms, oxygen is essential for efficient energy production but paradoxically,
produces chronic toxic stress in cells. Diverse protective systems must exist to enable …

Environmental factors and unhealthy lifestyle influence oxidative stress in humans—an overview

GSB Aseervatham, T Sivasudha, R Jeyadevi… - … Science and Pollution …, 2013 - Springer
Oxygen is the most essential molecule for life; since it is a strong oxidizing agent, it can
aggravate the damage within the cell by a series of oxidative events including the …

[HTML][HTML] Silybum marianum total extract, silymarin and silibinin abate hepatocarcinogenesis and hepatocellular carcinoma growth via modulation of the HGF/c-Met …

NYS Yassin, SF AbouZid, AM El-Kalaawy, TM Ali… - Biomedicine & …, 2022 - Elsevier
Hepatocellular carcinoma (HCC) has been identified as one of the most deadly
malignancies with limited therapeutic efficacy worldwide. However, understanding the …

Effects of occupational silica exposure on oxidative stress and immune system parameters in ceramic workers in Turkey

HG Anlar, M Bacanli, S İritaş, C Bal, T Kurt… - Journal of Toxicology …, 2017 - Taylor & Francis
Silica is the second most common element after oxygen, and therefore, exposures to
crystalline silica dust occur in a large variety of occupations such as metal foundries …

Melittin exerts beneficial effects on paraquat-induced lung injuries in mice by modifying oxidative stress and apoptosis

B El-Aarag, M Magdy, MF AlAjmi, SAM Khalifa… - Molecules, 2019 - mdpi.com
Melittin (MEL) is a 26-amino acid peptide with numerous biological activities. Paraquat (PQ)
is one of the most widely used herbicides, although it is extremely toxic to humans. To date …

Correlates of oxidative stress and free-radical activity in serum from asymptomatic shipyard welders

SG Han, Y Kim, ML Kashon, DL Pack… - American Journal of …, 2005 - atsjournals.org
Rationale: Oxidative stress is believed to play a key role in the development of welding-
induced disease. Objectives: This study investigated the effects of welding fume exposure …

Resveratrol and montelukast alleviate paraquat‐induced hepatic injury in mice: Modulation of oxidative stress, inflammation, and apoptosis

NA El-Boghdady, NF Abdeltawab… - Oxidative medicine and …, 2017 - Wiley Online Library
Paraquat (PQ) is one of the most used herbicide worldwide. Its cytotoxicity is attributed to
reactive radical generation. Resveratrol (Res) and montelukast (MK) have anti‐inflammatory …

Cytotoxicity evaluation and antioxidant enzyme expression related to heavy metals found in tuna by-products meal: an in vitro study in human and rat liver cell lines

SA Saïdi, MS Azaza, P Windmolders, J van Pelt… - Experimental and …, 2013 - Elsevier
Heavy metals can accumulate in organisms via various pathways, including respiration,
adsorption and ingestion. They are known to generate free radicals and induce oxidative …

Dose response chemopreventive potential of allyl isothiocyanate against 7, 12-dimethylbenz (a) anthracene induced mammary carcinogenesis in female Sprague …

T Rajakumar, P Pugalendhi, S Thilagavathi - Chemico-biological …, 2015 - Elsevier
The present study aimed to investigate the dose response chemopreventive potential of allyl
isothiocyanate (AITC) against 7, 12-dimethylbenz (a) anthracene (DMBA) induced mammary …

Plasma malondialdehyde and erythrocyte glutathione levels in workers with cement dust-exposure silicosis

A Orman, A Kahraman, H Çakar, H Ellidokuz… - Toxicology, 2005 - Elsevier
BACKGROUND:: Chronic exposure to cement dust has been reported to lead to several
health problems. Acute and chronic exposure to quartz are associated with the provocation …