[HTML][HTML] Endothelial dysfunction and immunothrombosis in sepsis

E Maneta, E Aivalioti, S Tual-Chalot… - Frontiers in …, 2023 - frontiersin.org
Sepsis is a life-threatening clinical syndrome characterized by multiorgan dysfunction
caused by a dysregulated or over-reactive host response to infection. During sepsis, the …

[HTML][HTML] The pathophysiology, diagnosis, and management of sepsis-associated disseminated intravascular coagulation

T Iba, J Helms, JM Connors, JH Levy - Journal of Intensive Care, 2023 - Springer
Abstract Background The International Society on Thrombosis and Haemostasis (ISTH)
released overt disseminated intravascular coagulation (DIC) diagnostic criteria in 2001 …

[HTML][HTML] Sepsis-induced coagulopathy: an update on pathophysiology, biomarkers, and current guidelines

AG Tsantes, S Parastatidou, EA Tsantes, E Bonova… - Life, 2023 - mdpi.com
Significant cross talk occurs between inflammation and coagulation. Thus, coagulopathy is
common in sepsis, potentially aggravating the prognosis. Initially, septic patients tend to …

[HTML][HTML] Guideline-based management of acute respiratory failure and acute respiratory distress syndrome

S Fujishima - Journal of intensive care, 2023 - Springer
Acute respiratory failure (ARF) is defined by acute and progressive hypoxemia caused by
various cardiorespiratory or systemic diseases in previously healthy patients. Among ARF …

[HTML][HTML] Intracellular communication and immunothrombosis in sepsis

T Iba, M Levi, JH Levy - Journal of Thrombosis and Haemostasis, 2022 - Elsevier
Inflammation and coagulation are the critical responses to infection that include leukocytes,
platelets, and vascular endothelial cells responding in concert to eradicate the invading …

Thromboinflammation in acute injury: infections, heatstroke, and trauma

T Iba, J Helms, M Levi, JH Levy - Journal of Thrombosis and Haemostasis, 2023 - Elsevier
Tissue microcirculation is essential for the maintenance of organ homeostasis. Following
acute infections, activation of coagulation and inflammation, which are critical …

Roles of coagulation abnormalities and microthrombosis in sepsis: pathophysiology, diagnosis, and treatment

T Iba, Y Umemura, H Wada, JH Levy - Archives of Medical Research, 2021 - Elsevier
The diagnostic criteria of overt disseminated intravascular coagulation (DIC) were
established by the International Society on Thrombosis and Haemostasis (ISTH) in 2001 …

[HTML][HTML] Communication from the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis on sepsis-induced …

T Iba, M Levi, J Thachil, J Helms, E Scarlatescu… - Journal of Thrombosis …, 2023 - Elsevier
Disseminated intravascular coagulation (DIC) is a life-threatening complication in sepsis
and other critical conditions. The International Society on Thrombosis and Haemostasis …

[HTML][HTML] Pathophysiology of disseminated intravascular coagulation in sepsis: a clinically focused overview

A Unar, L Bertolino, F Patauner, R Gallo… - Cells, 2023 - mdpi.com
Sepsis is a major global health problem that results from a dysregulated and uncontrolled
host response to infection, causing organ failure. Despite effective anti-infective therapy and …

[HTML][HTML] Association between the early mobilization of mechanically ventilated patients and independence in activities of daily living at hospital discharge

S Watanabe, J Hirasawa, Y Naito, M Mizutani… - Scientific Reports, 2023 - nature.com
Physical dysfunction after discharge from the intensive care unit (ICU) is recognized as a
common complication among ICU patients. Early mobilization (EM), defined as the ability to …