Glutamatergic neurons of the mammalian cerebral cortex originate from radial glia (RG)
progenitors in the ventricular zone (VZ). During corticogenesis, neuroblasts migrate toward …

microRNA-9-2 and microRNA-9-3 double-mutant mice demonstrate that microRNA-9 (miR-
9) controls neural progenitor proliferation and differentiation in the developing …

The evolution of the highest-order human brain center, the" pallium" or" cortex," remains
enigmatic. To elucidate its origins, we set out to identify related brain parts in …

Understanding brain development remains a major challenge at the heart of understanding
what makes us human. The neocortex, in evolutionary terms the newest part of the cerebral …

Increased cortical size is essential to the enhanced intellectual capacity of primates during
mammalian evolution. The mechanisms that control cortical size are largely unknown. Here …

BAF (Brg/Brm-associated factors) complexes play important roles in development and are
linked to chromatin plasticity at selected genomic loci. Nevertheless, a full understanding of …

The transcription factor Pax6 is comprised of the paired domain (PD) and homeodomain
(HD). In the developing forebrain, Pax6 is expressed in ventricular zone precursor cells and …

Activation of caged fluorophores in microscopy has mostly relied on the absorption of a
single ultraviolet (UV) photon of≲ 400 nm wavelength or on the simultaneous absorption of …

The transcription factor Pax6 has been implicated in neocortical neurogenesis in
vertebrates, including humans. Analyses of the role of Pax6 in layer formation and cognitive …

The transcription factor Pax6 is an important developmental regulator. Spatiotemporal
control of Pax6 expression during embryogenesis is crucial for regulating distinct aspects of …