Melatonin is a fascinating molecule that has captured the imagination of many scientists
since its discovery in 1958. In recent times, the focus has changed from investigating its …

Simple Summary Environmental light exposure is an important factor for human health that
impacts the biological clock of organisms. Melatonin usually serves as a chemical …

Aging has a major detrimental effect on the optimal function of the ovary with changes in this
organ preceding the age-related deterioration in other tissues, with the middle-aged …

Simple Summary Recent research suggests a strong link between the functioning of
mitochondria and the development of cancer. Healthy mitochondria play a vital role in …

Although previously restricted to a limited number of medical conditions, there is a growing
appreciation that 'autoimmune'(or immune-mediated) processes are important aspects of a …

Major depressive disorder (MDD) is widely accepted as having a heterogenous
pathophysiology involving a complex mixture of systemic and CNS processes. A …

Introduction Melatonin, originally isolated from the mammalian pineal gland, was
subsequently identified in many animal cell types and in plants. While melatonin was …

Head and neck squamous cell carcinoma present a high mortality rate. Melatonin has been
shown to have oncostatic effects in different types of cancers. However, inconsistent results …

There is a growing interest in the role of alterations in mitochondrial metabolism in the
pathoetiology and pathophysiology of cancers, including within the array of diverse cells that …

Type 1 diabetes mellitus (T1DM) arises from the failure of pancreatic β-cells to produce
adequate insulin, usually as a consequence of extensive pancreatic β-cell destruction …