Organoid cultures offer a valuable platform for studying organ-level biology, allowing for a
closer mimicry of human physiology compared to traditional two-dimensional cell culture …

Recent years have seen the creation and popularization of various complex in vitro models
(CIVMs), such as organoids and organs-on-chip, as a technology with the potential to …

Abstract Toll-like receptor 7 (TLR7) is known for eliciting immunity against single-stranded
RNA viruses, and is increased in both human and cigarette smoke (CS)-induced …

The symbiotic interplay of organoid technology and advanced imaging strategies yields
innovative breakthroughs in research and clinical applications. Organoids, intricate three …

Chronic obstructive pulmonary disease (COPD), a leading cause of morbidity and mortality
throughout the world, is a highly complicated disease that includes chronic airway …

Respiratory tissue engineering offers a robust framework for studying cell-cell and host-
pathogen interactions in a tissue-like environment and offers a platform for studying lung …

Lung organoids display a tissue-specific functional phenomenon and mimic the features of
the original organ. They can reflect the properties of the cells, such as morphology, polarity …

Whether and how microorganisms have shaped the evolution of their animal hosts is a
major question in biology. Although many animal evolutionary processes appear to correlate …

Background The fast-expanding global population, coupled with the threat of climate
change, have led to fresh challenges in meeting nutritional security. As a response to this …

Amidst the recent coronavirus disease 2019 (COVID-19) pandemic, respiratory system
research has made remarkable progress, particularly focusing on infectious diseases. Lung …