Mechanisms of hepatic triglyceride accumulation in non-alcoholic fatty liver disease
Y Kawano, DE Cohen - Journal of gastroenterology, 2013 - Springer
Non-alcoholic fatty liver disease (NAFLD) is characterized by hepatic lipid accumulation in
the absence of excess alcohol intake. NAFLD is the most common chronic liver disease, and …
the absence of excess alcohol intake. NAFLD is the most common chronic liver disease, and …
Membrane fatty acid transporters as regulators of lipid metabolism: implications for metabolic disease
JFC Glatz, JJFP Luiken, A Bonen - Physiological reviews, 2010 - journals.physiology.org
Long-chain fatty acids and lipids serve a wide variety of functions in mammalian
homeostasis, particularly in the formation and dynamic properties of biological membranes …
homeostasis, particularly in the formation and dynamic properties of biological membranes …
Diet-induced insulin resistance in mice lacking adiponectin/ACRP30
N Maeda, I Shimomura, K Kishida, H Nishizawa… - Nature medicine, 2002 - nature.com
Here we investigated the biological functions of adiponectin/ACRP30, a fat-derived
hormone, by disrupting the gene that encodes it in mice. Adiponectin/ACRP30-knockout …
hormone, by disrupting the gene that encodes it in mice. Adiponectin/ACRP30-knockout …
Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice
J Fruebis, TS Tsao, S Javorschi… - Proceedings of the …, 2001 - National Acad Sciences
Adipocyte complement-related protein (30 kDa)(Acrp30), a secreted protein of unknown
function, is exclusively expressed in differentiated adipocytes; its mRNA is decreased in …
function, is exclusively expressed in differentiated adipocytes; its mRNA is decreased in …
AMPK regulation of fatty acid metabolism and mitochondrial biogenesis: implications for obesity
Skeletal muscle plays an important role in regulating whole-body energy expenditure given
it is a major site for glucose and lipid oxidation. Obesity and type 2 diabetes are causally …
it is a major site for glucose and lipid oxidation. Obesity and type 2 diabetes are causally …
[HTML][HTML] Role of endogenous cannabinoids in synaptic signaling
TF Freund, I Katona, D Piomelli - Physiological reviews, 2003 - journals.physiology.org
Freund, Tamás F., István Katona, and Daniele Piomelli. Role of Endogenous Cannabinoids
in Synaptic Signaling. Physiol Rev 83: 1017–1066, 2003; 10.1152/physrev. 00004.2003 …
in Synaptic Signaling. Physiol Rev 83: 1017–1066, 2003; 10.1152/physrev. 00004.2003 …
Lipotoxic diseases
RH Unger - Annual review of medicine, 2002 - annualreviews.org
▪ Abstract I review evidence that leptin is a liporegulatory hormone that controls lipid
homeostasis in nonadipose tissues during periods of overnutrition. When adipocytes store …
homeostasis in nonadipose tissues during periods of overnutrition. When adipocytes store …
Genetic factors that affect risk of alcoholic and nonalcoholic fatty liver disease
Genome-wide association studies and candidate gene studies have informed our
understanding of factors contributing to the well-recognized interindividual variation in the …
understanding of factors contributing to the well-recognized interindividual variation in the …
SLC27 fatty acid transport proteins
CM Anderson, A Stahl - Molecular aspects of medicine, 2013 - Elsevier
The uptake and metabolism of long chain fatty acids (LCFA) are critical to many
physiological and cellular processes. Aberrant accumulation or depletion of LCFA underlie …
physiological and cellular processes. Aberrant accumulation or depletion of LCFA underlie …
[图书][B] Metabolic regulation: a human perspective
KN Frayn - 2013 - books.google.com
The important Third Edition of this successful book conveys a modern and integrated picture
of metabolism and metabolic regulation. Explaining difficult concepts with unequalled clarity …
of metabolism and metabolic regulation. Explaining difficult concepts with unequalled clarity …