Hemorrhagic fever with renal syndrome in Asia: history, pathogenesis, diagnosis, treatment, and prevention

A Sehgal, S Mehta, K Sahay, E Martynova, A Rizvanov… - Viruses, 2023 - mdpi.com
Hemorrhagic Fever with Renal Syndrome (HFRS) is the most frequently diagnosed zoonosis
in Asia. This zoonotic infection is the result of exposure to the virus-contaminated aerosols …

Hantavirus entry: Perspectives and recent advances

E Mittler, ME Dieterle, LM Kleinfelter, MM Slough… - Advances in virus …, 2019 - Elsevier
Hantaviruses are important zoonotic pathogens of public health importance that are found
on all continents except Antarctica and are associated with hemorrhagic fever with renal …

A replication-competent vesicular stomatitis virus for studies of SARS-CoV-2 spike-mediated cell entry and its inhibition

ME Dieterle, D Haslwanter, RH Bortz… - Cell host & …, 2020 - cell.com
There is an urgent need for vaccines and therapeutics to prevent and treat COVID-19. Rapid
SARS-CoV-2 countermeasure development is contingent on the availability of robust …

CCR2 is a host entry receptor for severe fever with thrombocytopenia syndrome virus

L Zhang, X Peng, Q Wang, J Li, S Lv, S Han… - Science …, 2023 - science.org
Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick-borne
bunyavirus causing a high fatality rate of up to 30%. To date, the receptor mediating SFTSV …

Structural and mechanistic basis of neutralization by a pan-hantavirus protective antibody

E Mittler, A Serris, ES Esterman, C Florez… - Science translational …, 2023 - science.org
Emerging rodent-borne hantaviruses cause severe diseases in humans with no approved
vaccines or therapeutics. We recently isolated a monoclonal broadly neutralizing antibody …

Recent advances in bunyavirus glycoprotein research: precursor processing, receptor binding and structure

RJG Hulswit, GC Paesen, TA Bowden, X Shi - Viruses, 2021 - mdpi.com
The Bunyavirales order accommodates related viruses (bunyaviruses) with segmented,
linear, single-stranded, negative-or ambi-sense RNA genomes. Their glycoproteins form …

Human antibody recognizing a quaternary epitope in the Puumala virus glycoprotein provides broad protection against orthohantaviruses

E Mittler, AZ Wec, J Tynell, P Guardado-Calvo… - Science translational …, 2022 - science.org
The rodent-borne hantavirus Puumala virus (PUUV) and related agents cause hemorrhagic
fever with renal syndrome (HFRS) in humans. Other hantaviruses, including Andes virus …

Orthohantavirus pathogenesis and cell tropism

D Noack, M Goeijenbier, CBEM Reusken… - Frontiers in cellular …, 2020 - frontiersin.org
Orthohantaviruses are zoonotic viruses that are naturally maintained by persistent infection
in specific reservoir species. Although these viruses mainly circulate among rodents …

The kidney in hantavirus infection—epidemiology, virology, pathophysiology, clinical presentation, diagnosis and management

FC Koehler, V Di Cristanziano, MR Späth… - Clinical kidney …, 2022 - academic.oup.com
Hantavirus-induced diseases are emerging zoonoses with endemic appearances and
frequent outbreaks in different parts of the world. In humans, hantaviral pathology is …

An overview of the infectious cycle of bunyaviruses

H Boshra - Viruses, 2022 - mdpi.com
Bunyaviruses represent the largest group of RNA viruses and are the causative agent of a
variety of febrile and hemorrhagic illnesses. Originally characterized as a single serotype in …