J Debnath, D Keshamasetthy, J Combs, K Leon… - Bioorganic …, 2024 - Elsevier
To investigate the intrinsic relation between carbonic anhydrase inhibition and anticancer activity, we have prepared four sets of diaryl urea molecules and tested for the inhibition of …
MI Konaklieva, BJ Plotkin - Applied Microbiology, 2023 - mdpi.com
β-Lactams in the last thirty years have been viewed as universal acylating agents of serine and cysteine enzymes of both prokaryotic and eukaryotic systems. More recently, their use …
T Matsutani, K Aoyama, T Moriuchi - Organometallics, 2023 - ACS Publications
A sustainable approach for the catalytic synthesis of unsymmetrical ureas from disilylamines through catalytic activation of carbon dioxide as a C1 building block under ambient pressure …
HY Lai, KH Yu, KC Tsai, CC Lee, HY Wang… - Bioorganic …, 2025 - Elsevier
Abstract Septin 9 (SEPT9), a GTPase, known as the fourth cytoskeleton, is widely expressed in various cells and tissues. The functions of SEPT9 are partly similar to other cytoskeletons …
A Catalano, D Iacopetta, M Pellegrino, S Aquaro… - 2021 - academia.edu
Antimicrobials have allowed medical advancements over several decades. However, the continuous emergence of antimicrobial resistance restricts efficacy in treating infectious …
AB Velappan, D Datta, R Ma, S Rana, KS Ghosh… - Bioorganic …, 2020 - Elsevier
The high mortality rate and the increasing prevalence of Mtb resistance are the major concerns for the Tuberculosis (TB) treatment in this century. To counteract the prevalence of …
AB Velappan, D Kesamsetty, D Datta, R Ma… - European Journal of …, 2020 - Elsevier
The high mortality rate and increasing prevalence of resistant Mtb are the major concerns for the Tuberculosis (TB) treatment in this century. To curtail the prevalence of resistant Mtb, we …
AB Velappan, S Kogatam, D Datta, R Srithar… - Organic Chemistry …, 2019 - pubs.rsc.org
Organic amines, in general, are protected through carbamate bond mediated cappings. Herein, we have demonstrated the chemically stable urea linkage suitably employed for …
AG Sarantou, G Varvounis - Molbank, 2022 - mdpi.com
For the synthesis of 1-(2-(1 H-pyrrole-2-carbonyl) phenyl)-3-(4-methoxyphenyl) urea, the final product, two different methods were used, in one or two steps, from (2-aminophenyl)(1 …