Introduction The preventive effects of chronic physical exercise (CPE) on Alzheimer's
disease (AD) are now admitted by the scientific community. Curative effects of CPE are more …

Understanding the causes of Alzheimer's disease and related dementias remains a
challenge. Observational studies investigating dementia risk factors are limited by the …

Physical activity and athletic performance are complex phenotypes influenced by
environmental and genetic factors. Recent advances in lifestyle and behavioral genomics …

Comorbidities associated with psychiatric disorders often occur in patients with cancer. A
causal effect of schizophrenia on cancer was observed using Mendelian randomization …

Uncovering causal relationships between exposures and outcomes can be difficult in
observational studies because of the potential for confounding and reverse causation to …

Aim The relationship between the gut microbiota, metabolites and body fat percentage (BFP)
remains unexplored. We systematically assessed the causal relationships between gut …

Background Cognitive function (CF) deterioration is a pressing concern in geriatric research.
This study aimed to explore the relationship between physical activity (PA) and CF in older …

This article is a comprehensive study based on research on the connection between
diabetes mellitus (DM) and prostate cancer (PCa). It investigates the potential role of DM as …

Background: The relationships of causality between physical activity and multisystem
diseases are still inconclusive. To evaluate the causal impact of physical activity on …