Folate deficiency enhances the in vitro genotoxicity of bile acids in human colon and liver cells

J Li, C Zhang, L Li, X Hu, Y Jia, Y Huang, T Lyu… - …, 2022 - academic.oup.com
Obese subjects have a high baseline of genotoxic stress, but the underlying mechanism is
poorly understood. Given that obesity is associated with high bile acids (BA) and low folate …

Long-term changes in the diurnal temporal regulation and set points of metabolic parameters associated with chronic maternal overnutrition in rabbits

E Navarrete, G Díaz, AM Salazar… - American Journal …, 2022 - journals.physiology.org
Metabolic syndrome (MS) and obesity have become a worldwide epidemic with an alarming
prevalence in women of reproductive age. Maternal metabolic condition is considered a risk …

A high-fat and high-carbohydrate diet promotes reminiscent hallmarks of an aging ovary in the rabbit model

V Díaz-Hernández, LM Montaño, I Caldelas… - Biomedicines, 2022 - mdpi.com
The primary definition of ovarian aging refers to the loss of follicles. Moreover, the aging of
the microenvironment in ovaries, specifically affecting the follicles, may reveal deterioration …

Stress in pregnancy alters hepatic unfolded protein responses in male adult offspring

GF Teixeira, J Mentzinger… - Molecular and Cellular …, 2025 - Elsevier
Stress is considered an independent risk factor for the development of cardiometabolic
disorders, especially when it occurs during pregnancy, and it may play an important role in …

[HTML][HTML] Delineation of the healthy rabbit liver by immunohistochemistry–A technical note

GM Bürgisser, O Evrova, DM Heuberger, J Rieber… - Acta …, 2021 - Elsevier
Liver diseases pose a big global health problem and liver failure may result from viral
infection, overnutrition or tumors. Studying pathologic liver tissue demands for accurate and …

The effect of maternal and early-life nutrition on redox homeostasis

U Ersoy, M Alameddine, I Kanakis, CA Staunton… - Modulation of Oxidative …, 2023 - Elsevier
Reactive oxygen species (ROS) serve as signaling molecules in the regulation of biological
and physiological processes. Fluctuations in ROS levels play a crucial role in cellular …