Many methods, including solid dispersion, micellization, and inclusion complexes, have
been employed to increase the solubility of potent drugs. Beta-cyclodextrin (βCD) is a cyclic …

Nanoemulsions have gained increasing attention in recent years as a drug delivery system
due to their ability to improve the solubility and bioavailability of poorly water-soluble drugs …

As the global population ages, the treatment of neurodegenerative diseases is becoming
more and more important. There is an urgent need to discover novel drugs that are effective …

Traumatic brain injury (TBI) is a significant cause of morbidity and mortality worldwide.
Varied mechanisms of injury contribute to the heterogeneity of this patient population as …

Traumatic brain injury (TBI) is a major cause of death and disability worldwide. There are no
effective therapies available for TBI patients. Vepoloxamer is an amphiphilic polyethylene …

Polymeric nanoparticles are among the most widely used nanocarriers for delivering
therapeutic molecules. However, their synthesis processes often generate undesirable …

Introduction: In this case study, a client-owned dog with a large pituitary tumor was
experimentally treated by intratumoral injection of radioactive holmium-166 microspheres …

Aim Voriconazole (VRZ) is highly effective in treating invasive pulmonary aspergillosis (IPA),
in addition to hepatotoxicity. Therefore, the current study focuses on the development and …

Abstract Traumatic Brain Injury (TBI) is a major cause of severe disability and death,
resulting in significant health care and economic burden. Poloxamer 188, a synthetic tri …

Background: Mitochondrial dysfunction, which is triggered by systemic ischemia–reperfusion
(IR) injury and affects various organs, is a key factor in the development of post-cardiac …