Highlights•PFPs are fundamental defense and virulence factors in bacteria and as executors
of regulated cell death in eukaryotic cells.•Proteins and lipids cooperate to form different …

Despite an enhanced permeability and retention effect typical of many solid tumors, drug
penetration is not always sufficient. Possible strategies for the drug delivery improvement …

Streptomyces griseus trypsin (SGT) possesses enzymatic properties similar to mammalian
trypsins and has great potential applications in the leather processing, bioethanol, detergent …

Sea anemones (Cnidaria, Anthozoa, and Actiniaria) use toxic peptides to incapacitate and
immobilize prey and to deter potential predators. Their toxin arsenal is complex, targeting a …

Transcriptomic profiling of venom producing tissues from different animals is an effective
approach for discovering new toxins useful in biotechnological and pharmaceutical …

Actinoporins (APs) are a family of pore-forming toxins (PFTs) from sea anemones. These
biomolecules exhibit the ability to exist as soluble monomers within an aqueous medium or …

Sea anemone actinoporins constitute a protein family of multigene pore-forming toxins
(PFT). Equinatoxin II (EqtII), fragaceatoxin C (FraC), and sticholysins I and II (StnI and StnII …

Sea anemones produce pore-forming toxins, actinoporins, which are interesting as tools for
cytoplasmic membranes study, as well as being potential therapeutic agents for cancer …

Actinoporins constitute a unique class of pore-forming toxins found in sea anemones that
are able to bind and oligomerize in membranes, leading to cell swelling, impairment of ionic …

Sticholysins are pore-forming toxins of biomedical interest and represent a prototype of
proteins acting through the formation of protein-lipid or toroidal pores. Peptides spanning the …