The ability of a healthy immune system to clear the plethora of antigens it encounters
incessantly relies on the enormous plasticity displayed by the comprising cell types …

Lipoproteins, namely high-density lipoproteins (HDL), transport a wide-variety of cargo in
addition to cholesterol and lipids. In 2011, HDL and low-density lipoproteins (LDL) were …

Regulatory T cells (Treg) are a subpopulation of T cells that maintain tolerance to self and
limit other immune responses. They achieve this through different mechanisms including the …

We have shown that endogenous neurosteroids, including pregnenolone and 3α, 5α-THP
inhibit toll-like receptor 4 (TLR4) signal activation in mouse macrophages and the brain of …

Human amniotic membrane-derived mesenchymal stromal cells (hAMSCs) are easily
obtained in large quantities and free from ethical concerns. Promising therapeutic results for …

MicroRNAs (miRNAs) are critical regulators of the host immune and inflammatory response
against bacterial pathogens. In the present review, we discuss target genes, target gene …

Background MicroRNAs have emerged as an important class of modulators of gene
expression. These molecules influence protein synthesis through translational repression or …

Emerging evidence suggests comprehensive immune profiling represents a highly
promising, yet insufficiently tapped approach to identify potentially prognostic signatures for …

Tumor-associated macrophages (TAM) are causally associated with tumorigenesis as well
as regulation of antitumor immune responses and have emerged as potential …

An increasing body of literature is addressing the immuno-modulating functions of miRNAs
which include paracrine signaling via exosome-mediated intercellular miRNA. In view of the …