Immunobiology of varicella-zoster virus infection

KJ Laing, WJD Ouwendijk, DM Koelle… - The Journal of …, 2018 - academic.oup.com
Varicella-zoster virus (VZV) causes clinically significant illness during acute and recurrent
infection accompanied by robust innate and acquired immune responses. Innate immune …

A comparison of herpes simplex virus type 1 and varicella-zoster virus latency and reactivation

PGE Kennedy, J Rovnak… - Journal of General …, 2015 - microbiologyresearch.org
Herpes simplex virus type 1 (HSV-1; human herpesvirus 1) and varicella-zoster virus (VZV;
human herpesvirus 3) are human neurotropic alphaherpesviruses that cause lifelong …

Brain immune cells undergo cGAS/STING-dependent apoptosis during herpes simplex virus type 1 infection to limit type I IFN production

LS Reinert, AS Rashidi, DN Tran… - The Journal of …, 2021 - Am Soc Clin Investig
Protection of the brain from viral infections involves the type I IFN (IFN-I) system, defects in
which render humans susceptible to herpes simplex encephalitis (HSE). However …

An alternative pathway of enteric PEDV dissemination from nasal cavity to intestinal mucosa in swine

Y Li, Q Wu, L Huang, C Yuan, J Wang… - Nature communications, 2018 - nature.com
Porcine epidemic diarrhea virus (PEDV) has catastrophic impacts on the global pig industry.
Although the fecal–oral route is generally accepted, an increased number of reports indicate …

Manipulation of the innate immune response by varicella zoster virus

C Gerada, TM Campbell, JJ Kennedy… - Frontiers in …, 2020 - frontiersin.org
Varicella zoster virus (VZV) is the causative agent of chickenpox (varicella) and shingles
(herpes zoster). VZV and other members of the herpesvirus family are distinguished by their …

A spliced latency-associated VZV transcript maps antisense to the viral transactivator gene 61

DP Depledge, WJD Ouwendijk, T Sadaoka… - Nature …, 2018 - nature.com
Abstract Varicella-zoster virus (VZV), an alphaherpesvirus, establishes lifelong latent
infection in the neurons of> 90% humans worldwide, reactivating in one-third to cause …

Molecular aspects of varicella-zoster virus latency

DP Depledge, T Sadaoka, WJD Ouwendijk - Viruses, 2018 - mdpi.com
Primary varicella-zoster virus (VZV) infection causes varicella (chickenpox) and the
establishment of a lifelong latent infection in ganglionic neurons. VZV reactivates in about …

An In Vitro Model of Latency and Reactivation of Varicella Zoster Virus in Human Stem Cell-Derived Neurons

A Markus, I Lebenthal-Loinger, IH Yang… - PLoS …, 2015 - journals.plos.org
Varicella zoster virus (VZV) latency in sensory and autonomic neurons has remained
enigmatic and difficult to study, and experimental reactivation has not yet been achieved. We …

[HTML][HTML] Varicella zoster virus in the nervous system

D Gilden, M Nagel, R Cohrs, R Mahalingam… - …, 2015 - ncbi.nlm.nih.gov
Varicella zoster virus (VZV) is a ubiquitous, exclusively human alphaherpesvirus. Primary
infection usually results in varicella (chickenpox), after which VZV becomes latent in …

Varicella zoster virus productively infects human peripheral blood mononuclear cells to modulate expression of immunoinhibitory proteins and blocking PD-L1 …

D Jones, CN Como, L Jing, A Blackmon, CP Neff… - PLoS …, 2019 - journals.plos.org
Varicella zoster virus (VZV) is a lymphotropic alpha-herpesvirinae subfamily member that
produces varicella on primary infection and causes zoster, vascular disease and vision loss …