Genetic polymorphisms associated with rheumatoid arthritis development and antirheumatic therapy response

DS Mikhaylenko, MV Nemtsova, IV Bure… - International journal of …, 2020 - mdpi.com
Rheumatoid arthritis (RA) is the most common inflammatory arthropathy worldwide. Possible
manifestations of RA can be represented by a wide variability of symptoms, clinical forms …

Identification of diagnostic biomarkers for idiopathic pulmonary hypertension with metabolic syndrome by bioinformatics and machine learning

W Lu, J Huang, Q Shen, F Sun, J Li - Scientific Reports, 2023 - nature.com
Idiopathic pulmonary hypertension (IPAH) is a condition that affects various tissues and
organs and the metabolic and inflammatory systems. The most prevalent metabolic …

Common marker genes identified from various sample types for systemic lupus erythematosus

PF Bing, W Xia, L Wang, YH Zhang, SF Lei, FY Deng - PLoS One, 2016 - journals.plos.org
Objective Systemic lupus erythematosus (SLE) is a complex auto-immune disease. Gene
expression studies have been conducted to identify SLE-related genes in various types of …

Elevated serum TREM-1 is associated with periodontitis and disease activity in rheumatoid arthritis

N Inanc, G Mumcu, M Can, M Yay, A Silbereisen… - Scientific reports, 2021 - nature.com
The triggering receptor expressed on myeloid cells 1 (TREM-1) and peptidoglycan
recognition protein 1 (PGLYRP1) are involved in the propagation of inflammatory responses …

Serum PGLYRP‑1 is a highly discriminatory biomarker for the diagnosis of rheumatoid arthritis

Q Luo, X Li, L Zhang, F Yao… - Molecular …, 2019 - spandidos-publications.com
Abstract Peptidoglycan recognition protein‑1 (PGLYRP‑1) is a part of the innate immune
system. It is well‑known that dysregulation of innate immune responses is present in patients …

Effect of selected single nucleotide polymorphisms in SLC11A1, ANKRA2, IFNG and PGLYRP1 genes on host susceptibility to Mycobacterium avium subspecies …

B Gopi, R Vir Singh, S Kumar, S Kumar… - Veterinary research …, 2022 - Springer
Paratuberculosis (PTB) is a chronic infectious enteritis of ruminants, caused by
Mycobacterium avium subspecies paratuberculosis (MAP) that brings huge economic loss to …

[PDF][PDF] Elevated expression of Pglyrp1 in peripheral blood mononuclear cells and PGLYRP-1 in serum from systemic lupus erythematosus patients

Q Luo, FY Yao, L Zhang, X Li, C Qing, RG Su… - Int J Clin Exp …, 2019 - e-century.us
Background: Peptidoglycan recognition protein-1 (PGLYRP-1) is part of the innate immune
system. It has been established that disorders of innate immune response are found in …

[PDF][PDF] Human peptidoglycan recognition protein 1 in innate immunity

J Yang - Cogent Biology, 2018 - scholar.archive.org
Peptidoglycan recognition proteins (PGRPs) are innate immunity proteins that are
conserved from insects to mammals. Related research results show the functions of …

GWAS of Clinically Defined Gout Identifies Non-Urate-Related Loci and Implicates Novel Gene, Pathway and Cell Type Associations

C Li, L Han, C Wang, Z Zhou, C Wu, J Lu, L Cui, Z Liu… - 2022 - papers.ssrn.com
Background: Gout is most common inflammatory arthritis characterized by deposition of
monosodium urate crystals in joints. Several genome-wide association studies (GWAS) …