Trypanosoma brucei, as well as Trypanosoma cruzi and more than 20 species of the genus
Leishmania, form a group of flagellated protists that threaten human health. These …

Highlights•Host AMPK, mTOR and HIF-1α are key regulators of Leishmania
infection.•Leishmania hijacks amino acid metabolism to proliferate inside the …

Glutamine synthetase (GS) is a key enzyme responsible for the incorporation of inorganic
nitrogen in the form of ammonium into the amino acid glutamine. In plants, two groups of …

The pearl oyster Pinctada fucata martensii is a warm-water shellfish that is sensitive to cold
environments. To investigate its potential adaptation to low-temperature stress, the selected …

Glutamine synthetase (GS) is one of the most important metabolic enzymes which catalyzes
ligation of glutamate and ammonia to form glutamine. Previous studies from our lab had …

Abstract Pyridoxal kinase (PdxK, EC 2.7. 1.35) is an important enzyme of vitamin B6 salvage
pathway which is required for phosphorylation of B6 vitamers. In the present study, pyridoxal …

In the present study, a quantitative proteomic approach to study changes in saliva proteins
associated with canine leishmaniosis (CanL) was performed. For this, canine salivary …

Trypanosoma cruzi, the etiological agent of Chagas disease, consumes glucose and amino
acids depending on the environmental availability of each nutrient during its complex life …

Leishmania, a protozoan parasite inflicting the complex of diseases called Leishmaniases,
resides and replicates as amastigotes within mammalian macrophages. As macrophages …

Leishmaniasis is a major health problem with 600k-1M new cases worldwide and 1 billion at
risk. It involves a wide range of clinical forms ranging from self-healing cutaneous lesions to …