With an increasingly aging society, bone defects and fractures have become significant
threats to human health and quality of life. Currently, autologous and allogeneic bone grafts …

The complex interaction of cells with biomaterials (ie, materiobiology) plays an increasingly
pivotal role in the development of novel implants, biomedical devices, and tissue …

Monocyte‐derived macrophages (MDMs) generated from peripheral blood monocytes are
widely used to model human macrophages for in vitro studies. However, the possible impact …

Adverse immune reactions prevent clinical translation of numerous implantable devices and
materials. Although inflammation is an essential part of tissue regeneration, chronic …

Macrophages play a central role in orchestrating immune responses to foreign materials,
which are often responsible for the failure of implanted medical devices. Material topography …

Implanted biomaterials often fail because they elicit a foreign body response (FBR) and
concomitant fibrotic encapsulation. To design clinically relevant interference approaches, it …

The immune system protects organisms against endogenous and exogenous harm and
plays a key role in tissue development, repair and regeneration. Traditional …

Biological studies on the importance of carbohydrate moieties in tissue engineering have
incited a growing interest in the application of polysaccharides as scaffolds over the past two …

Macrophages play a crucial rule in orchestrating immune responses against pathogens and
foreign materials. Macrophages have remarkable plasticity in response to environmental …

Photoresponsive materials have been widely used in vitro for controlled therapeutic delivery
and to direct 4D cell fate. Extension of the approaches into a bodily setting requires use of …