The transient receptor potential (TRP) ion channels are named after the discovery of the
photo-transducted channels in Drosophila. TRPs, activated by various extracellular and …

Stroke is a devastating medical condition, killing millions of people each year and causing
serious injury to many more. Despite advances in treatment, there is still little that can be …

St. John's wort is an herb, long used in folk medicine for the treatment of mild depression. Its
antidepressant constituent, hyperforin, has properties such as chemical instability and …

Ischemic stroke is one of the most disabling diseases and a leading cause of death globally.
Despite advances in medical care, the global burden of stroke continues to grow, as no …

To date, miRNA expression studies on cerebral ischemia in both human and animal models
have focused mainly on acute phase of ischemic stroke. In this study, we present the roles …

Transient receptor potential (TRP) family proteins form tetrameric nonselective cation
channels. Upon activation, TRP channels depolarize the membrane potential, which can …

The seven canonical members of transient receptor potential (TRPC) proteins form cation
channels that evoke membrane depolarization and intracellular calcium concentration …

Transient receptor potential canonical 6 (TRPC6) channel is an important non-selective
cation channel with a variety of physiological roles in the central nervous system. Evidence …

Epigenetic regulations including DNA methylation and demethylation play critical roles in
neural development. However, whether DNA methylation and demethylation may play a role …

Allergy and autoimmune diseases are characterised by a multifactorial pathogenic
background. Several genes involved in the control of innate and adaptive immunity have …