[HTML][HTML] Protein transduction domain-mediated delivery of recombinant proteins and in vitro transcribed mRNAs for protein replacement therapy of human severe …

AN Miliotou, PF Foltopoulou, A Ingendoh-Tsakmakidis… - Pharmaceutics, 2023 - mdpi.com
Mitochondrial disorders represent a heterogeneous group of genetic disorders with
variations in severity and clinical outcomes, mostly characterized by respiratory chain …

Recruiting In Vitro Transcribed mRNA against Cancer Immunotherapy: A Contemporary Appraisal of the Current Landscape

AN Miliotou, SK Georgiou-Siafis, C Ntenti… - Current Issues in …, 2023 - mdpi.com
Over 100 innovative in vitro transcribed (IVT)-mRNAs are presently undergoing clinical trials,
with a projected substantial impact on the pharmaceutical market in the near future. Τhe idea …

Pink1 gene: a key player in the pathophysiology of type 2 diabetes mellitus

K Dinislam, P Egor, H Arina, K Sergienko… - Egyptian …, 2024 - journals.lww.com
Type 2 diabetes mellitus (T2DM) is a complicated metabolic condition with insulin resistance
and poor glucose metabolism. Emerging evidence indicates the significance of (PTEN …

[PDF][PDF] Technologien und Lösungsansätze für die effiziente Herstellung von Zelltherapeutika für die CAR-Immuntherapie

U Blache, K Kebbel, A Quaiser, G Popp… - Gen-und Zelltherapie …, 2023 - library.oapen.org
Patientenzahl in der Zukunft gewährleistet werden kann und welche Hürden es dabei zu
überwinden gilt, wird im Folgenden adressiert. Erste Optionen zur automatisierten …